Evidence map›Paper›PMID 37384267›Full record

ArticleJournal of liver cancer2021

Hepatocellular Carcinoma in Korea: an Analysis of the 2015 Korean Nationwide Cancer Registry.

Jun Sik Yoon, Han Ah Lee, Hwi Young Kim, Dong Hyun Sinn, Dong Ho Lee, Suk Kyun Hong, Ju-Yeon Cho, Jonggi Choi, Young Chang, Hyun-Joo Kong and 3 more

RetractedAbstract read
In one paragraph

Article in Journal of liver cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  13. A Case of Transverse Myelitis Following Treatment with Atezolizumab for Advanced Hepatocellular Carcinoma.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Jun Sik YoonDepartment of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Han Ah LeeDepartment of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
Hwi Young KimDepartment of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.
Dong Hyun SinnDepartment of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Dong Ho LeeDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.
Suk Kyun HongDepartment of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Ju-Yeon ChoDepartment of Medicine, Chosun University, Gwangju, Korea.
Jonggi ChoiDepartment of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Young ChangInstitute for Digestive Research, Digestive Disease Center, Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.
Hyun-Joo KongCancer Registration and Statistic Branch, National Cancer Control Institute, National Cancer Center, Goyang, Korea.
Eunyang KimCancer Registration and Statistic Branch, National Cancer Control Institute, National Cancer Center, Goyang, Korea.
Young-Joo WonCancer Registration and Statistic Branch, National Cancer Control Institute, National Cancer Center, Goyang, Korea.
Jeong-Hoon LeeLiver Research Institute, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID 0000-0002-0315-2080

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aims: Hepatocellular carcinoma (HCC) is the sixth most common cancer and the second leading cause of cancer-related death in Korea. This study evaluated the characteristics of Korean patients newly diagnosed with HCC in 2015. Methods: Data from the Korean Primary Liver Cancer Registry (KPLCR), a representative sample of patients newly diagnosed with HCC in Korea, were analyzed. A total of 1,558 patients with HCC registered in the KPLCR in 2015 were investigated. Results: The median age was 61.0 years (interquartile range, 54.0-70.0 years), and men accounted for 79.7% of the subjects. Hepatitis B virus infection was the most common underlying liver disease (58.1%). According to the Barcelona Clinic Liver Cancer (BCLC) staging system, stage 0, A, B, C, and D HCCs accounted for 14.2%, 31.5%, 7.6%, 39.0%, and 7.8% of patients, respectively. Transarterial therapy (32.1%) was the most commonly performed initial treatment, followed by surgical resection (23.2%), best supportive care (20.2%), and local ablation therapy (10.7%). Overall, 34.5% of patients were treated in accordance with the BCLC guidelines: 59.2% in stage 0/A, 48.4% in stage B, 18.1% in stage C, and 71.6% in stage D. The 1-, 3-, and 5-year OS rates were 67.1%, 50.9%, and 27.0%, respectively. Conclusions: In 2015, approximately 45% of Korean HCC cases were diagnosed at a very early or early stage, and 35% of patients underwent potentially curative initial treatment. BCLC guidance was followed in 34.5% of patients; in patients with stage B or C disease, there was relatively low adherence.

Indexed as

EpidemiologyHepatitis BHepatocellular carcinomaKoreaSurvival

Identifiers

PMID37384267
PMCPMC10035724

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.