Evidence map›Paper›PMID 37384203›Full record

ArticleCase reports in oncology

Surgical Treatment of Hepatocellular Carcinoma with a Tumor Thrombus Invading the Right Atrium: A Case Report.

Laura Veinberga, Kristians Meidrops, Roberts Rumba, Marcis Gedins, Deniss Anufrijevs, Janis Vilmanis, Karina Drizlionoka, Edgars Zellans, Inguna Krustina, Juris Berzins and 5 more

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In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. The role of cuproptosis in gastric cancer.Frontiers in immunology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Laura VeinbergaDepartment of Surgery, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Kristians MeidropsDepartment of Surgery, Riga Stradins University, Riga, Latvia.
Roberts RumbaDepartment of Vascular Surgery, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Marcis GedinsDepartment of Vascular Surgery, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Deniss AnufrijevsDepartment of Surgery, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Janis VilmanisDepartment of Surgery, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Karina DrizlionokaDepartment of Cardiac Anaesthesia and Intensive Care, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Edgars ZellansDepartment of Cardiac Anaesthesia and Intensive Care, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Inguna KrustinaDepartment of Cardiac Anaesthesia and Intensive Care, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Juris BerzinsDiagnostic Radiology Institute, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Inese BriedeDepartment of Pathology, Riga Stradins University, Riga, Latvia.
Armands SivinsClinic of Surgical Oncology, Riga East Clinical University Hospital, Riga, Latvia.
Maija RadzinaRadiology Research Laboratory, Riga Stradins University, Riga, Latvia.
Peteris StradinsDepartment of Surgery, Riga Stradins University, Riga, Latvia.
Arturs OzolinsDepartment of Surgery, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Pauls Stradiņš Clinical University Hospital · LVRiga East University Hospital · LV

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Up to 3% of all hepatocellular carcinomas (HCCs) present with a tumor thrombus (TT) in the inferior vena cava (IVC) and right atrium (RA). Extensive growth of HCC into the IVC and the RA is associated with a particularly poor prognosis. This clinical condition is related to a high risk of sudden death due to pulmonary embolism or acute heart failure. Therefore, a technically challenging treatment undergoing hepatectomy and cavo-atrial thrombectomy is necessary. We report a 61-year-old man presenting with right subcostal pain, progressive weakness, and periodic shortness of breath for 3 months. He was diagnosed with advanced HCC with a TT extending from the right hepatic vein into the IVC and RA. A multidisciplinary meeting with cardiovascular and hepatobiliary surgeons, oncologists, cardiologists, anesthesiologists, and radiologists was held to determine the best treatment approach. Initially, the patient underwent right hemihepatectomy. As follows, the cardiovascular stage using cardiopulmonary bypass was successfully performed, removing the TT from the RA and ICV. In the early postoperative period, the patient remained stable and was discharged on the 8th postoperative day. A morphological examination revealed grade 2/3 HCC, a clear cell variant with microvascular and macrovascular invasion. Immunohistochemical staining was positive for HEP-1, CD10, whereas negative for S100. The morphological and immunohistochemical results corresponded to HCC. The treatment of such patients requires the cooperation of various specialties. Although the approach of the surgery is extremely complex including specific technical support, as well as high perioperative risks, the result offers favorable clinical outcomes.

Indexed as

Cavo-atrial thrombectomyHepatocellular carcinomaLiver resectionRight atriumTumor thrombus

Identifiers

PMID37384203
PMCPMC10294241
OpenAlexW4381162390

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.