Evidence map›Paper›PMID 37384115›Full record

ArticleInternational journal of general medicine2023

Shikonin Inhibits

Chong Pang, Jianshuang Chen, Lan Yang, Yang Yang, Haihua Qi, Ran Li, Yingying Cao, Hao Miao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of general medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. StudyingPharmaceuticals (Basel, Switzerland) · 2025
    Review
  3. Inhibition of Biofilm Formation inInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Chong PangSchool of Basic Medicine, Chengde Medical University, Chengde, Hebei, People's Republic of China.
Jianshuang ChenSchool of Basic Medicine, Chengde Medical University, Chengde, Hebei, People's Republic of China.
Lan YangHebei Key Laboratory of Research and Development for Chinese Medicine, Chengde Medical University, Chengde, Hebei, People's Republic of China.
Yang YangSchool of Basic Medicine, Chengde Medical University, Chengde, Hebei, People's Republic of China.
Haihua QiDepartment of Dermatology, Affiliated Hospital of Chengde Medical University, Chengde, Hebei, People's Republic of China.
Ran LiSchool of Basic Medicine, Chengde Medical University, Chengde, Hebei, People's Republic of China.
Yingying CaoShanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, People's Republic of China.
Hao MiaoSchool of Basic Medicine, Chengde Medical University, Chengde, Hebei, People's Republic of China.ORCID 0000-0002-6393-0753
Chengde Medical University · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the influence of shikonin (SK) on the formation of Methods: The inhibition of the formation of Results: The results showed that SK could destroy the typical three-dimensional structure of the biofilms, inhibit cell surface hydrophobicity and cell adhesion, downregulate the expression of Ras1-cAMP-Efg1 signalling pathway-related genes ( Conclusion: Our results suggest that SK exhibits potential anti-

Indexed as

biofilmsCandida albicansRas1-cAMP-Efg1 signalling pathwayshikonin

Identifiers

PMID37384115
PMCPMC10296564
OpenAlexW4381805544

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.