Evidence map›Paper›PMID 37383618›Full record

ReviewFrontiers in psychiatry2023

Transcriptomics and magnetic resonance imaging in major psychiatric disorders.

Jing-Wen Fan, Yue-Wen Gu, Dong-Bao Wang, Xiao-Fan Liu, Shu-Wan Zhao, Xiao Li, Baojuan Li, Hong Yin, Wen-Jun Wu, Long-Biao Cui

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Multi-omics approaches to major psychiatric disorders.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2026
    Review
  2. Article
  3. Frontiers in psychiatry · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Jing-Wen FanDepartment of Clinical Psychology, Fourth Military Medical University, Xi'an, China.
Yue-Wen GuDepartment of Clinical Psychology, Fourth Military Medical University, Xi'an, China.
Dong-Bao WangSchizophrenia Imaging Lab, Fourth Military Medical University, Xi'an, China.
Xiao-Fan LiuDepartment of Clinical Psychology, Fourth Military Medical University, Xi'an, China.
Shu-Wan ZhaoDepartment of Clinical Psychology, Fourth Military Medical University, Xi'an, China.
Xiao LiDepartment of Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Baojuan LiSchool of Biomedical Engineering, Fourth Military Medical University, Xi'an, China.
Hong YinDepartment of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Wen-Jun WuDepartment of Psychiatry, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Long-Biao CuiDepartment of Clinical Psychology, Fourth Military Medical University, Xi'an, China.
Air Force Medical University · CNXijing Hospital · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CNThe Affiliated Yongchuan Hospital of Chongqing Medical University · CNXi’an Children’s Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Major psychiatric disorders create a significant public health burden, and mental disorders such as major depressive disorder, bipolar disorder, and schizophrenia are major contributors to the national disease burden. The search for biomarkers has been a leading endeavor in the field of biological psychiatry in recent decades. And the application of cross-scale and multi-omics approaches combining genes and imaging in major psychiatric studies has facilitated the elucidation of gene-related pathogenesis and the exploration of potential biomarkers. In this article, we summarize the results of using combined transcriptomics and magnetic resonance imaging to understand structural and functional brain changes associated with major psychiatric disorders in the last decade, demonstrating the neurobiological mechanisms of genetically related structural and functional brain alterations in multiple directions, and providing new avenues for the development of quantifiable objective biomarkers, as well as clinical diagnostic and prognostic indicators.

Indexed as

bipolar disordermajor depressive disorderMRIschizophreniatranscriptomics

Identifiers

PMID37383618
PMCPMC10296768
OpenAlexW4380085077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.