Evidence map›Paper›PMID 37383559›Full record

ArticleThe Lancet regional health. Southeast Asia2023

Seroprevalence and prevention of hepatitis B, measles and rubella among healthcare workers in Dili, Timor-Leste.

Celia Gusmao, Maria Y Tanesi, Nelia Gomes, Sarah L Sheridan, Nevio Sarmento, Tessa Oakley, Michael David, Johanna Wapling, Lucsendar Alves, Salvador Amaral and 9 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Lancet regional health. Southeast Asia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 3 countries.

Celia GusmaoHospital Nacional Guido Valadares, Dili, Timor-Leste.
Maria Y TanesiMenzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
Nelia GomesMenzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
Sarah L SheridanNational Centre for Immunisation Research and Surveillance, Westmead, NSW, Australia.
Nevio SarmentoMenzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
Tessa OakleyMenzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
Michael DavidDaffodil Centre, The University of Sydney, A Joint Venture with Cancer Council New South Wales, Sydney, NSW, Australia.
Johanna WaplingMenzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
Lucsendar AlvesMenzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
Salvador AmaralMenzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
Anthony D K DraperMenzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
Bernardino CruzMinistry of Health, Dili, Timor-Leste.
Danina CoelhoMinistry of Health, Dili, Timor-Leste.
Helio GuterresHospital Nacional Guido Valadares, Dili, Timor-Leste.
Nicholas S S FancourtMenzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
Jennifer YanMenzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
Kristine MacartneyNational Centre for Immunisation Research and Surveillance, Westmead, NSW, Australia.
Joshua R FrancisMenzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
Paul ArkellMenzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
Charles Darwin University · AUMenzies School of Health Research · AUUniversidade da Paz · TLGriffith University · AUNational Centre for Immunisation Research & Surveillance · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The World Health Organisation recommends that healthcare workers (HCWs) are immune to measles and rubella, and those at risk of exposure are offered the hepatitis B vaccine. No formal programme for occupational assessment and provision of vaccinations to HCWs currently exists in Timor-Leste. Methods: A cross-sectional study was undertaken to determine the seroprevalence of hepatitis B, measles and rubella among HCWs in Dili, Timor-Leste. All patient-facing employees at three healthcare institutions during April-June 2021 were invited to participate. Epidemiological data were collected by interview-questionnaire and a serum sample was collected by phlebotomy and analysed at the National Health Laboratory. Participants were contacted to discuss their results. Relevant vaccines were offered to seronegative individuals and those with active hepatitis B infection were referred for further assessment and management in a hepatology clinic as per national guidelines. Results: Three-hundred-and-twenty-four HCWs were included (representing 51.3% of all eligible HCWs working at the three participating institutions). Sixteen (4.9%; 95% CI: 2.8-7.9%) had active hepatitis B infection, 121 (37.3%; 95% CI: 32.1-42.9%) had evidence of previous (cleared) hepatitis B infection, 134 (41.4%; 95% CI: 35.9-46.9%) were hepatitis B seronegative, and 53 (16.4%; 95% CI: 12.5-20.8%) had been vaccinated. Two-hundred-and-sixty-seven (82.4%; 95% CI: 77.8-86.4%) and 306 (94.4%; 95% CI: 91.4-96.7%) individuals exhibited antibodies to measles and rubella, respectively. Interpretation: There are significant immunity gaps and a high prevalence of hepatitis B infection among HCWs in Dili Municipality, Timor-Leste. Routine occupational assessment and targeted vaccination of this group would be beneficial and should include all types of HCWs. This study provided an opportunity to develop a programme for the occupational assessment and vaccination of HCWs and forms the template for a national guideline. Funding: This work was supported by the Department of Foreign Affairs and Trade, Australian Government [Complex Grant Agreement Number 75889].

Indexed as

Healthcare workerHepatitis BMeaslesOccupational healthRubellaSerological surveillanceVaccinationVaccine preventable diseases

Identifiers

PMID37383559
PMCPMC10305905
OpenAlexW4317038157

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.