ArticleBrain & spine2023
Increasing incidence of spondylodiscitis in England: An analysis of the national health service (NHS) hospital episode statistics from 2012 to 2021.
Article in Brain & spine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 47 citations in OpenAlex.
- Temporal trends in incidence, clinical characteristics and outcomes of pyogenic vertebral osteomyelitis in Southern Denmark from 2009 to 2022: a retrospective population-based cohort study.Annals of medicine · 2026Article
- When infection becomes architecture: structural predictors of surgical management in spondylodiscitis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- External Validation of the SITE Score for De Novo Spinal Infections: A Retrospective Cohort Study.Global spine journal · 2026Article
- Infectious Spondylodiscitis of Bacterial Causes in Adults: Epidemiology, Pathophysiology, Diagnostic and Treatment Challenges.Microorganisms · 2026Review
- Prediction and risk factors for one year mortality in patients after surgery for pyogenic spondylodiscitis.Neurosurgical review · 2026Article
- Secondary changes in sagittal alignment after instrumented surgery with and without corpectomy for pyogenic spondylodiscitis.Brain & spine · 2026Article
- Clinical and radiological features of infectious spondylodiscitis in an Italian cohort: a retrospective study.Brain & spine · 2026Article
- Clinical characteristics, microbiological landscape, and severity-stratified management of pyogenic spondylitis: a retrospective cohort study.Frontiers in cellular and infection microbiology · 2026Observational
- Risk factors for revision surgery due to construct failure after instrumented treatment of pyogenic spondylodiscitis.Brain & spine · 2026Article
- Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2025Article
- Spondylodiscitis associated with recurrentBJR case reports · 2025Article
- Changing Tides in the Treatment of Spondylodiscitis? A Retrospective, Monocentric Comparison of Mortality and Quality of Life After Surgical and Conservative Treatment.Clinics and practice · 2025Article
- The Patients´ quality of life and outcome after surgical treatment for primary spinal infection.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Pyogenic Spondylodiscitis: Predictors of Microbiological Yield from Biopsy in a Tertiary Hospital.Medicina (Kaunas, Lithuania) · 2025Article
- What Is Worse: A Comparison of Solitary Versus Multifocal Pyogenic Spondylodiscitis Using a Nationwide Analysis of Readmission Rates and Risk Factors.Journal of clinical medicine · 2025Article
- Vertebral osteomyelitis in patients with an underlying malignancy or chronic kidney disease - who is at higher risk for adverse outcome?Infection · 2025Article
- Surgical treatment of unstable spondylodiscitis with posterior instrumentation and bioactive glass (BAG-S53P4): surgical technique and results at medium-term follow-up.Journal of spine surgery (Hong Kong) · 2025Article
- Spondylodiscitis relevant tissue concentrations of cefuroxime - a large animal microdialysis study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Posterior fixation without debridement for pyogenic spondylodiscitis can promote infection control: initial evaluation of a pyogenic spondylodiscitis posterior fixation rat model.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- The conundrum of finding an optimal spondylodiscitis treatment pathway: how do treatments affect readmission rates?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Spondylodiscitis is a potentially life-threatening infection of the intervertebral disk and adjacent vertebral bodies, with a mortality rate of 2-20%. Given the aging population, the increase in immunosuppression, and intravenous drug use in England, the incidence of spondylodiscitis is postulated to be increasing; however, the exact epidemiological trend in England remains unknown. Objective: The Hospital Episode Statistics (HES) database contains details of all secondary care admissions across NHS hospitals in England. This study aimed to use HES data to characterise the annual activity and longitudinal change of spondylodiscitis in England. Methods: The HES database was interrogated for all cases of spondylodiscitis between 2012 and 2019. Data for the length of stay, waiting time, age-stratified admissions, and 'Finished Consultant Episodes' (FCEs), which correspond to a patient's hospital care under a lead clinician, were analysed. Results: In total, 43135 FCEs for spondylodiscitis were identified between 2012 and 2022, of which 97.1% were adults. Overall admissions for spondylodiscitis have risen from 3 per 100,000 population in 2012/13 to 4.4 per 100,000 population in 2020/21. Similarly, FCEs have increased from 5.8 to 10.3 per 100,000 population, in 2012-2013 and 2020/21 respectively. The highest increase in admissions from 2012 to 2021 was recorded for those aged 70-74 (117% increase) and aged 75-59 (133% increase), among those of working age for those aged 60-64 years (91% increase). Conclusion: Population-adjusted admissions for spondylodiscitis in England have risen by 44% between 2012 and 2021. Healthcare policymakers and providers must acknowledge the increasing burden of spondylodiscitis and make spondylodiscitis a research priority.
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