Evidence map›Paper›PMID 37383332›Full record

ArticleWorld journal of otorhinolaryngology - head and neck surgery2023

Significance of age and sex in botulinum neurotoxin dosing for adductor spasmodic dysphonia.

Richard Heyes, Charles H Adler, Nan Zhang, David G Lott, Stephen F Bansberg

Open access · goldAbstract read
In one paragraph

Article in World journal of otorhinolaryngology - head and neck surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Significance of age and sex in botulinum neurotoxin dosing for adductor spasmodic dysphonia.World journal of otorhinolaryngology - head and neck surgery · 2023
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Richard HeyesDepartment of Otorhinolaryngology - Head and Neck Surgery Mayo Clinic Arizona Phoenix Arizona USA.ORCID 0000-0002-6923-3131
Charles H AdlerDepartment of Neurology Mayo Clinic Arizona Phoenix Arizona USA.
Nan ZhangDepartment of Biostatistics and Bioinformatics Mayo Clinic Arizona Phoenix Arizona USA.
David G LottDepartment of Otorhinolaryngology - Head and Neck Surgery Mayo Clinic Arizona Phoenix Arizona USA.
Stephen F BansbergDepartment of Otorhinolaryngology - Head and Neck Surgery Mayo Clinic Arizona Phoenix Arizona USA.
WinnMed · USMayo Clinic Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aims to analyze the impact of age and sex on botulinum neurotoxin (BoNT-A) dosing and outcomes in adductor spasmodic dysphonia (AdSD). Methods: A database review of all spasmodic dysphonia patients treated with BoNT from 1989 to 2018 at the Mayo Clinic in Arizona was performed. Only patients who had received ≥4 injections of BoNT-A for AdSD were included. Patients were divided into two cohorts to analyze age, with an age of first treatment cutoff of 60 years. Patients were divided into male and female cohorts to analyze sex. Results: The final analysis included 398 patients. The mean dose of BoNT-A per treatment was significantly higher in the younger cohort (4.4 vs. 3.9 units, Conclusions: This study suggests that age and sex influence BoNT-A dosing and outcomes in AdSD.

Indexed as

adductoragegenderoutcomessexspasmodic dysphonia

Identifiers

PMID37383332
PMCPMC10296044
OpenAlexW4319789156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.