SynthesisFrontiers in public health2023
Global and regional estimates of clinical and economic burden of low back pain in high-income countries: a systematic review and meta-analysis.
Synthesis in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
103 citing papers in PubMed, 6 syntheses or guidelines pooled it, 131 citations in OpenAlex.
- Cost-effectiveness of artificial intelligence interventions for musculoskeletal disorders of the spine: a systematic review.Rheumatology international · 2026Pooled it
- Effectiveness of high-intensity laser therapy in patients with spinal radiculopathy: a systematic review with meta-analysis.Lasers in medical science · 2025Pooled it
- Effect of Motivational Interviewing and Exercise on Chronic Low Back Pain: A Systematic Review and Meta-Analysis.Musculoskeletal care · 2025Pooled it
- Health service utilization for low back pain in Germany between 2000 and 2020-a scoping review of claims data.Frontiers in pain research (Lausanne, Switzerland) · 2025Pooled it
- The effectiveness of non-pharmacological interventions for low back pain in China: A systematic review and network meta-analysis.PloS one · 2025Pooled it
- How non-specific low back pain affects gait kinematics: a systematic review and meta-analysis.Frontiers in pain research (Lausanne, Switzerland) · 2025Pooled it
- Cost-effectiveness of Pilates compared with home-based exercises for people with chronic non-specific low back pain: a trial-based economic evaluation.BMC musculoskeletal disorders · 2026Trial
- Aquatic therapy compared to standard care for chronic low back pain: a randomized controlled trial.Pain management · 2026Trial
- Trial
- Cost-utility analysis of acupotomy combined with epidural steroid injection for lumbosacral radiculopathy: analysis of randomized controlled trial.BMC complementary medicine and therapies · 2025Trial
- Lumbar stabilization exercise with and without real-time ultrasound imaging biofeedback in chronic low back pain patients: a randomized controlled trial.Scientific reports · 2025Trial
- Impact of Intramuscular Electrical Stimulation on Multifidus Muscle Function in Chronic Low Back Pain: A Randomized Controlled Trial.Medical science monitor : international medical journal of experimental and clinical research · 2025Trial
- Digitally supported physical activity counselling for people with chronic back pain: a randomised controlled parallel feasibility study.BMC primary care · 2025Trial
- Musculoskeletal Disorders: From Molecular Pathology to Novel Therapeutic Approach.International journal of molecular sciences · 2026Article
- Comparison of the Effects of Kinesio Taping and Foam Roller Exercises in Individuals with Non-Specific Chronic Low Back Pain.Healthcare (Basel, Switzerland) · 2026Article
- Article
- Cost savings and quality-of-life gains associated with the use of an AI-powered digital tool for self-management of chronic pain based on a multicenter cohort study.Pain medicine (Malden, Mass.) · 2026Article
- Article
- Observational
- Age-referenced modeling of lumbar disc degeneration and its association with chronic low back pain: an MRI-based cross-sectional study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
43 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Low back pain (LBP) is a common health problem, and the leading cause of activity limitation and work absence among people of all ages and socioeconomic strata. This study aimed to analyse the clinical and economic burden of LBP in high income countries (HICs) via systematic review and meta-analysis. Methods: A literature search was carried out on PubMed, Medline, CINAHL, PsycINFO, AMED, and Scopus databases was from inception to March 15th, 2023. Studies that assessed the clinical and economic burden of LBP in HICs and published in English language were reviewed. The methodological quality of the included studies was assessed using the Newcastle-Ottawa quality assessment scale (NOS) for cohort studies. Two reviewers, using a predefined data extraction form, independently extracted data. Meta-analyses were conducted for clinical and economic outcomes. Results: The search identified 4,081 potentially relevant articles. Twenty-one studies that met the eligibility criteria were included and reviewed in this systematic review and meta-analysis. The included studies were from the regions of America ( Discussion: Low back pain led to high clinical and economic burden in HICs that varied significantly across the geographical contexts. The results of our analysis can be used by clinicians, and policymakers to better allocate resources for prevention and management strategies for LBP to improve health outcomes and reduce the substantial burden associated with the condition. Systematic review registration: https://www.crd.york.ac.uk/prospero/#recordDetails?, PROSPERO [CRD42020196335].
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.