Evidence map›Paper›PMID 37383224›Full record

ArticleFrontiers in immunology2023

IP3R-dependent mitochondrial dysfunction mediates C5b-9-induced ferroptosis in trichloroethylene-caused immune kidney injury.

Zhibing Liu, Jinru Ma, Xulei Zuo, Xuesong Zhang, Haibo Xie, Feng Wang, Changhao Wu, Jiaxiang Zhang, Qixing Zhu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Zhibing LiuDepartment of Dermatology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Jinru MaDepartment of Occupational Health and Environmental Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
Xulei ZuoDepartment of Occupational Health and Environmental Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
Xuesong ZhangDepartment of Occupational Health and Environmental Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
Haibo XieDepartment of Nephropathy, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Feng WangDepartment of Dermatology, Second Hospital of Anhui Medical University, Hefei, Anhui, China.
Changhao WuSchool of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom.
Jiaxiang ZhangDepartment of Occupational Health and Environmental Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
Qixing ZhuDepartment of Dermatology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Anhui Medical University · CNFirst Affiliated Hospital of Anhui Medical University · CNSecond Affiliated Hospital of Anhui Medical University · CNUniversity of Surrey · GB

Funding

Nox Enzymes in Aging Bladder DysfunctionR01AG049321 · NIA · TEMPLE UNIV OF THE COMMONWEALTH · PI BARBE, MARY F · 2016 to 2020
$1.7M
Biotechnology and Biological Sciences Research Council BB/P004695/1NIA NIH HHS R01 AG049321
6 · The paper itself

Abstract

Patients with occupational medicamentose-like dermatitis due to trichloroethylene often suffer from immune kidney injury. Our previous study reveals that C5b-9-dependent cytosolic Ca

Indexed as

FerroptosisTrichloroethyleneAnimalsComplement Membrane Attack ComplexKidneyMiceMitochondriaMitochondrial Permeability Transition PoreComplement Membrane Attack ComplexMitochondrial Permeability Transition PoreTrichloroethyleneC5b-9ferroptosisIP3Rmitochondrial dysfunctionoccupational medicamentose-like dermatitis due to trichloroethylene

Identifiers

PMID37383224
PMCPMC10294229
OpenAlexW4380632943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.