ArticleClinical oral investigations2023
Evaluation of dentinal tubule occlusion and pulp tissue response after using 980-nm diode laser for dentin hypersensitivity treatment.
Article in Clinical oral investigations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- The comparison of lasers and topical desensitizing agents in the management of dentin hypersensitivity: a systematic review and meta-analysis.Clinical oral investigations · 2025Pooled it
- Clinical evaluation of the effect of 980 nm diode laser and fluoride varnish on dentin hypersensitivity.Brazilian oral research · 2025Trial
- Evaluation of Three Methods for the Treatment of Dentin Hypersensitivity: A Randomised Clinical Trial.International dental journal · 2024Trial
- Trial
- One-Year Clinical Performance of Injectable and Paste-Type Composite Resins in Non-Carious Cervical Lesions Prepared with Er,Cr:YSGG Laser and Acid Etching: A Randomized Clinical Trial.Journal of functional biomaterials · 2026Article
- Comparative evaluation of dentinal tubule occlusion by desensitizing agents after tooth bleaching: an in vitro study.Restorative dentistry & endodontics · 2026Article
- Effect of laser applications with different agents on dentin surface roughness, bacterial adhesion and tubule occlusion.Clinical oral investigations · 2025Article
- Photothermal Effect and Biomineralization of Black Phosphorus Nanosheet-Composited Hydrogel Boosts Synergistic Treatment of Dentin Hypersensitivity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Casein Phosphopeptide and Diode Laser in Treating Dentin Hypersensitivity: A Clinical Study.Journal of lasers in medical sciences · 2025Article
- The Efficacy of Different Laser Applications on Dentin Sealing in Preventing Discoloration Induced by Mineral Trioxide Aggregate.Materials (Basel, Switzerland) · 2024Article
- A Review on Enhancing the Life of Teeth by Toothpaste Containing Bioactive Glass Particles.Current oral health reports · 2024Review
- Enhancing the inhibition of dental erosion and abrasion with quercetin-encapsulated hollow mesoporous silica nanocomposites.Frontiers in bioengineering and biotechnology · 2024Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
objectivesTo evaluate the effectiveness of the 980-nm diode laser for dentinal tubule occlusion, measure the intrapulpal temperature, and investigate the dental pulp response. MATERIALS AND
methodsThe dentinal samples were randomly divided into G1-G7 groups: control; 980-nm laser irradiation (0.5 W, 10 s; 0.5 W, 10 s × 2; 0.8 W, 10 s; 0.8 W, 10 s × 2; 1.0 W, 10 s; 1.0 W, 10 s × 2). The dentin discs were applied for laser irradiation and analyzed by scanning electron microscopy (SEM). The intrapulpal temperature was measured on the 1.0-mm and 2.0-mm thickness samples, and then divided into G2-G7 groups according to laser irradiation. Moreover, forty Sprague Dawley rats were randomly divided into the laser-irradiated group (euthanized at 1, 7, and 14 days after irradiation) and the control group (non-irradiated). qRT-PCR, histomorphology, and immunohistochemistry analysis were employed to evaluate the response of dental pulp.
resultsSEM indicated the occluding ratio of dentinal tubules in the G5 (0.8 W, 10 s × 2) and G7 (1.0 W, 10 s × 2) were significantly higher than the other groups (p < 0.05). The maximum intrapulpal temperature rises in the G5 were lower than the standard line (5.5 ℃). qRT-PCR showed that the mRNA expression level of TNF-α and HSP-70 upregulated significantly at 1 day (p < 0.05). Histomorphology and immunohistochemistry analysis showed that, compared with the control group, the inflammatory reaction was slightly higher at the 1 and 7 days (p < 0.05) and decreased to the normal levels at 14 days (p > 0.05).
conclusionsA 980-nm laser at a power of 0.8 W with 10 s × 2 defines the best treatment for dentin hypersensitivity in terms of compromise between the efficacy of the treatment and the safety of the pulp. CLINICAL RELEVANCE: The 980-nm laser is an effective option for treating dentin sensitivity. However, we need to ensure the safety of the pulp during laser irradiation.
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