Evidence map›Paper›PMID 37382653›Full record

ArticleAnalytical and bioanalytical chemistry2023

A sample-preparation-free, point-of-care testing system for in situ detection of bovine mastitis.

Lei He, Bing Chen, Yu Hu, Boheng Hu, Ya Li, Xiaonan Yang

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lei HeSchool of Electrical and Information Engineering, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Bing ChenDepartment of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Yu HuSchool of Electrical and Information Engineering, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Boheng HuSchool of Electrical and Information Engineering, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Ya LiDepartment of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China. liya0305@126.com.
Xiaonan YangSchool of Electrical and Information Engineering, Zhengzhou University, Zhengzhou, 450001, Henan, China. iexnyang@zzu.edu.cn.
Zhengzhou University · CNFirst Affiliated Hospital of Zhengzhou University · CN

Funding

Strategic Priority Research Program of the Chinese Academy of Sciences XDB44000000The Science and Technology Research Program of Henan Province 232102311187
6 · The paper itself

Abstract

We present a highly integrated point-of-care testing (POCT) device capable of immediately and accurately screening bovine mastitis infection based on somatic cell counting (SCC). The system primarily consists of a homemade cell-counting chamber and a miniature fluorescent microscope. The cell-counting chamber is pre-embedded with acridine orange (AO) in advance, which is simple and practical. And then SCC is directly identified by microscopic imaging analysis to evaluate the bovine mastitis infection. Only 4 μL of raw bovine milk is required for a simple sample testing and accurate SCC. The entire assay process from sampling to result in presentation is completed quickly within 6 min, enabling instant "sample-in and answer-out." Under laboratory conditions, we mixed bovine leukocyte suspension with whole milk and achieved a detection limit as low as 2.12 × 10

Indexed as

Mastitis, BovineAnimalsCattleCell CountFemaleMicroscopy, FluorescenceMilkPoint-of-Care TestingBovine mastitisFluorescent stainingMicroscopic imaging analysisPoint-of-care testingSomatic cell counting

Identifiers

PMID37382653
OpenAlexW4382501753

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.