Evidence map›Paper›PMID 37382263›Full record

ReviewImmunity, inflammation and disease2023

Liposomal delivery system/adjuvant for tuberculosis vaccine.

Melika Moradi, Farzaneh Vahedi, Arian Abbassioun, Arash Ramezanpour Shahi, Mohammad Sholeh, Mortaza Taheri-Anganeh, Zahra Dargahi, Roya Ghanavati, Seyyed Hossein Khatami, Ahmad Movahedpour

Open access · goldAbstract readReview
In one paragraph

Review in Immunity, inflammation and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  9. Liposomal delivery system/adjuvant for tuberculosis vaccine.Immunity, inflammation and disease · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Melika MoradiDepartment of Microbiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Farzaneh VahediDepartment of Medical Biotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran.
Arian AbbassiounDepartment of Virology, Faculty of Veterinary Medicene, University of Tehran, Tehran, Iran.
Arash Ramezanpour ShahiDepartment of Veterinary Clinical Sciences, Poultry diseases and hygiene Resident, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran.
Mohammad SholehDepartment of Bacteriology, Pasteur Institute of Iran, Tehran, Iran.
Mortaza Taheri-AnganehCellular and Molecular Research Center, Cellular and Molecular Medicine Research Institute, Urmia University of Medical Sciences, Urmia, Iran.
Zahra DargahiDepartment of Microbiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Roya GhanavatiBehbahan Faculty of Medical Sciences, Behbahan, Iran.
Seyyed Hossein KhatamiDepartment of Clinical Biochemistry, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ahmad MovahedpourBehbahan Faculty of Medical Sciences, Behbahan, Iran.ORCID 0000-0002-0576-4435
Ahvaz Jundishapur University of Medical Sciences · IRPasteur Institute of Iran · IRShahid Beheshti University of Medical Sciences · IRShahrekord University · IRShiraz University of Medical Sciences · IRUniversity of Tehran · IRUrmia University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As reported by the World Health Organization, about 10 million individuals were infected with tuberculosis (TB) worldwide. Moreover, approximately 1.5 million people died of TB, of which 214,000 were infected with HIV simultaneously. Due to the high infection rate, the need for effective TB vaccination is highly felt. Until now, various methodologies have been proposed for the development of a protein subunit vaccine for TB. These vaccines have shown higher protection than other vaccines, particularly the Bacillus culture vaccine. The delivery system and safety regulator are common characteristics of effective adjuvants in TB vaccines and the clinical trial stage. The present study investigates the current state of TB adjuvant research focusing on the liposomal adjuvant system. Based on our findings, the liposomal system is a safe and efficient adjuvant from nanosize to microsize for vaccinations against TB, other intracellular infections, and malignancies. Clinical studies can provide valuable feedback for developing novel TB adjuvants, which ultimately enhance the impact of adjuvants on next-generation TB vaccines.

Indexed as

Tuberculosis VaccinesAdjuvants, ImmunologicHumansVaccinationAdjuvants, ImmunologicTuberculosis VaccinesMycobacterium tuberculosissubunit vaccinevaccination

Identifiers

PMID37382263
PMCPMC10251763
OpenAlexW4380088012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.