Evidence map›Paper›PMID 37382209›Full record

ArticleJournal of surgical oncology2023

Postoperative complications in women with ovarian cancer stratified by cytoreductive surgery outcome.

Rosa M Polan, Jennifer M Slota, Emma L Barber

Open access · greenAbstract read
In one paragraph

Article in Journal of surgical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Rosa M PolanDivision of Gynecology Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, USA.ORCID http://orcid.org/0000-0001-8738-3187
Jennifer M SlotaDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, Northwestern University, Chicago, Illinois, USA.
Emma L BarberDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, Northwestern University, Chicago, Illinois, USA.
Northwestern University · USWayne State University · US

Funding

The Claude D. Pepper Older Americans Independence Center (OAIC) at Northwestern UniversityP30AG059988 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CELLA, DAVID · 2020 to 2024
$7.1M
A PILOT STUDY OF PREHABILITATION DURING THE NEOADJUVANT WINDOW OF OPPORTUNITY IN OLDER WOMEN WITH OVARIAN CANCER (FIT4SURGERY)R03AG074031 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BARBER, EMMA · 2021 to 2022
$320k
NIA NIH HHS P30 AG059988NIA NIH HHS R03 AG074031
6 · The paper itself

Abstract

objectiveTo compare 30-day postoperative complications for patients with advanced ovarian cancer who underwent resection to no gross residual disease versus optimal and suboptimal cytoreduction.

methodsA retrospective cohort study of women drawn from the National Surgical Quality Improvement Program who underwent cytoreductive surgery for advanced ovarian cancer between 2014 and 2019 was performed. Exposure of interest was extent of surgical resection defined as no gross residual disease; residual disease <1 cm (optimal); and residual disease >1 cm (suboptimal). Primary outcome was postoperative complication. Associations were examined with bivariable tests and multivariable logistic regression.

resultsA total of 2248 women underwent cytoreductive surgery; 68.4% (n = 1538) underwent resection to no gross residual disease, 22.4% (n = 504) had an optimal, and 9.2% (n = 206) had a suboptimal cytoreduction. Optimal cytoreduction patients had the highest rates of any postoperative complication (35.5%, p < 0.001). They also had the longest operative times and procedures that were most surgically complex (203 min, 43.6 relative value units, both p < 0.05). However, patients who underwent optimal cytoreduction did not have increased odds of major complications (adjusted odds ratio: 1.20, 95% confidence interval: 0.91-1.58).

conclusionPatients who underwent optimal cytoreduction had more postoperative complications, required the most operating room time, and represented more complex surgeries compared with suboptimal cytoreduction or resection to no gross residual disease.

Indexed as

Cytoreduction Surgical ProceduresOvarian NeoplasmsCarcinoma, Ovarian EpithelialFemaleHumansPostoperative ComplicationsRetrospective Studiescytoreductiondebulkingno gross residualoptimalovarian cancersuboptimal

Identifiers

PMID37382209
PMCPMC10529113
OpenAlexW4382501273

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.