Evidence map›Paper›PMID 37382139›Full record

ArticleJournal of the American Heart Association2023

Cardiac Cachexia in Left Ventricular Assist Device Recipients and the Implications of Weight Gain Early After Implantation.

Amanda R Vest, Lori Lyn Price, Anindita Chanda, Benjamin A Sweigart, Joronia Chery, Matthew Lawrence, Lauren Parsly, Gaurav Gulati, Michael S Kiernan, Jenica N Upshaw and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Amanda R VestCardioVascular Center Tufts Medical Center Boston MA USA.ORCID 0000-0001-8274-5660
Lori Lyn PriceTufts Clinical and Translational Science Institute Tufts University Boston MA USA.ORCID 0000-0003-0664-8978
Anindita ChandaDepartment of Medicine University of Connecticut Hartford CT USA.ORCID 0000-0002-8543-7978
Benjamin A SweigartTufts Clinical and Translational Science Institute Tufts University Boston MA USA.ORCID 0000-0002-3837-3289
Joronia CheryCardioVascular Center Tufts Medical Center Boston MA USA.ORCID 0000-0001-9038-5239
Matthew LawrenceCardioVascular Center Tufts Medical Center Boston MA USA.ORCID 0009-0008-6298-892X
Lauren ParslyFrances Stern Nutrition Center Tufts Medical Center Boston MA USA.
Gaurav GulatiCardioVascular Center Tufts Medical Center Boston MA USA.ORCID 0000-0002-7701-0878
Michael S KiernanCardioVascular Center Tufts Medical Center Boston MA USA.ORCID 0000-0003-4026-6383
Jenica N UpshawCardioVascular Center Tufts Medical Center Boston MA USA.
Masashi KawaboriCardioVascular Center Tufts Medical Center Boston MA USA.ORCID 0000-0002-3580-5664
Gregory S CouperCardioVascular Center Tufts Medical Center Boston MA USA.
Edward SaltzmanFriedman School of Nutrition Science and Policy at Tufts University Boston MA USA.ORCID 0000-0002-3626-1195
Tufts Medical Center · USTufts University · USUniversity of Connecticut · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Severe cardiac cachexia or malnutrition are commonly considered relative contraindications to left ventricular assist device (LVAD) implantation, but post-LVAD prognosis for patients with cachexia is uncertain. Methods and Results Intermacs (Interagency Registry for Mechanically Assisted Circulatory Support) 2006 to 2017 was queried for the preimplantation variable cachexia/malnutrition. Cox proportional hazards modeling examined the relationship between cachexia and LVAD outcomes. Of 20 332 primary LVAD recipients with available data, 516 (2.54%) were reported to have baseline cachexia and had higher risk baseline characteristics. Cachexia was associated with higher mortality during LVAD support (unadjusted hazard ratio [HR], 1.36 [95% CI, 1.18-1.56];

Indexed as

Heart-Assist DevicesHeart FailureMalnutritionCachexiaHumansRegistriesRetrospective StudiesTreatment Outcomecachexiaheart failuremalnutritionmechanical circulatory support

Identifiers

PMID37382139
PMCPMC10356076
OpenAlexW4382502690

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.