Evidence map›Paper›PMID 37381780›Full record

ArticlePsychological medicine2023

A longitudinal comparison of emotional, behavioral and attention problems in autistic and typically developing children.

N Wright, V Courchesne, A Pickles, R Bedford, E Duku, C M Kerns, T Bennett, S Georgiades, J Hill, A Richard and 8 more

Abstract read
In one paragraph

Article in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Double-blind, sham-controlled, pilot study of trigeminal nerve stimulation for autism spectrum disorder.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Methodological challenges and opportunities when studying the course of autism.Autism : the international journal of research and practice · 2025
    Article
  9. Trajectories of positive affect in autistic individuals during the transition to adulthood.Autism : the international journal of research and practice · 2025
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

N WrightDepartment of Psychology, Manchester Metropolitan University, Manchester, UK.ORCID 0000-0002-3285-2051
V CourchesneCentre for Addiction and Mental Health, University of Toronto, Toronto, Canada.
A PicklesDepartment of Biostatistics & Health Informatics, King's College London, London, UK.
R BedfordDepartment of Psychology, University of Bath, Bath, UK.
E DukuMcMaster University, Hamilton, Canada.
C M KernsDepartment of Psychology, University of British Columbia, Vancouver, Canada.
T BennettMcMaster University, Hamilton, Canada.
S GeorgiadesMcMaster University, Hamilton, Canada.
J HillSchool of Psychology & Clinical Language Sciences, University of Reading, Reading, UK.
A RichardIWK Health Centre, Autism Research Centre, Halifax, Canada.
H SharpDepartment of Primary Care and Mental Health, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.
I M SmithDalhousie University and IWK Health, Halifax, Canada.
T VaillancourtUniversity of Ottawa, Ottawa, Canada.
A Zaidman-ZaitTel Aviv University, Tel Aviv, Israel.
L ZwaigenbaumUniversity of Alberta, Alberta, Canada.
P SzatmariCentre for Addiction and Mental Health, University of Toronto, Toronto, Canada.
M ElsabbaghDepartment of Neurology and Neurosurgery, McGill University, Montreal, Canada.
Pathways Team

Funding

Medical Research Council MR/L022257/1Medical Research Council MR/L022257/2
6 · The paper itself

Abstract

backgroundMental health problems are elevated in autistic individuals but there is limited evidence on the developmental course of problems across childhood. We compare the level and growth of anxious-depressed, behavioral and attention problems in an autistic and typically developing (TD) cohort.

methodsLatent growth curve models were applied to repeated parent-report Child Behavior Checklist data from age 2-10 years in an inception cohort of autistic children (Pathways,

resultsAutistic children showed elevated levels of mental health problems, but this was substantially reduced by accounting for IQ and sex differences between the autistic and TD samples. There was small differences in growth patterns; anxious-depressed problems were particularly elevated at preschool and attention problems at late childhood. Higher family income predicted lower base-level on all three dimensions, but steeper increase of anxious-depressed problems. Higher IQ predicted lower level of attention problems and faster decline over childhood. Female sex predicted higher level of anxious-depressed and faster decline in behavioral problems. Social-affect autism symptom severity predicted elevated level of attention problems. Autistic girls' problems were particularly elevated relative to their same-sex non-autistic peers.

conclusionsAutistic children, and especially girls, show elevated mental health problems compared to TD children and there are some differences in predictors. Assessment of mental health should be integrated into clinical practice for autistic children.

Indexed as

Autistic DisorderProblem BehaviorAttentionChildChild, PreschoolEmotionsFemaleHumansMaleParentsattention problemsAutismbehavioral problemsemotional problemslongitudinaltrajectories

Identifiers

PMID37381780
PMCPMC10755241

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.