SynthesisBMC oral health2023
Dental arch spatial changes after premature loss of first primary molars: a systematic review and meta-analysis of split-mouth studies.
Synthesis in BMC oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06573463 (Longevity of Prefabricated Band and Loop Versus Conventional Band and Loop Space Maintainers in Children With Prematurely Lost First Primary Molars), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Longevity of Prefabricated Band and Loop Versus Conventional Band and Loop Space Maintainers in Children With Prematurely Lost First Primary Molars
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Extraction of first primary molars and significance of space loss: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Preventive and Interceptive Orthodontic Treatment Needs in Early and Late Mixed Dentition: An IPION-Based Assessment in Children.Children (Basel, Switzerland) · 2026Article
- Global Research Trends in Pediatric Space Maintainers: A Bibliometric Analysis of Web of Science Literature.Cureus · 2026Article
- Review
- Radiographic study of mandibular alterations resulting from aketogenic diet in growing rats.Acta odontologica latinoamericana : AOL · 2026Article
- A Simplified Technique for the Fabrication of Esthetic and Functional Space Maintainers in Pediatric Dentistry.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026Article
- Review
- Review
- Effectiveness of Space Maintainers in Pediatric Patients: A Systematic Review and Meta-Analysis.Dentistry journal · 2025Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to evaluate spatial changes in dental arches resulting from premature loss of first primary molars and assess the necessity of a space maintainer.
methodsWe searched the electronic databases PubMed, Cochrane Library, ClinicalTrials, and EMBASE. Split-mouth studies involving unilateral premature loss of a primary first molar were included. Quality assessment of selected studies made use of the ROBINS-I tool. Mean space differences were calculated for the D + E and D spaces, arch width, arch length, arch perimeter.
resultsOf the 329 studies considered, 11 split-mouth studies were selected, including 246 cases in the maxilla and 217 in the mandible from 477 individuals aged 5-10 years. Over the medium-term follow-up period (6-24 months), space loss was 0.65 mm in the maxillary D + E (MD 0.65, 95% CI 0.15-1.16, P = 0.01), 1.24 mm in the mandibular D + E (MD 1.24, 95% CI 0.60-1.89, P < 0.01), and 1.47 mm in the mandibular D (MD 1.47, 95% CI 0.66-2.28, P < 0.01). There was no significant change in arch width, length, or arch perimeter between the initial and follow-up examinations (P > 0.05).
conclusionsAfter premature loss of first primary molars, space can be lost, but the amount of loss would not affect arch width, length, or arch perimeter over the 6-24 months follow-up period.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.