Evidence map›Paper›PMID 37380914›Full record

ArticleInternational journal of clinical pharmacy2023

Adherence to oral endocrine therapy in racial/ethnic minority patients with low socioeconomic status before and during the COVID-19 pandemic.

Sama Rahimi, Onyebuchi Ononogbu, Anjana Mohan, Daniel Moussa, Susan Abughosh, Meghana V Trivedi

Open access · hybridAbstract read
In one paragraph

Article in International journal of clinical pharmacy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Interventions to improve adherence to oral endocrine therapy for prevention or treatment of breast cancer in Black women of low socioeconomic status.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Interventions to improve oral endocrine therapy adherence in breast cancer patients.Journal of cancer survivorship : research and practice · 2025
    Review
  10. Immunomodulator adherence in multiple myeloma patients with lower socioeconomic status: a retrospective study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sama RahimiDepartment of Pharmacy Practice and Translational Research, University of Houston, College of Pharmacy, Health 2, 4349 Martin Luther King Blvd, Houston, TX, 77204-5000, USA.
Onyebuchi OnonogbuDepartment of Pharmacy Practice and Translational Research, University of Houston, College of Pharmacy, Health 2, 4349 Martin Luther King Blvd, Houston, TX, 77204-5000, USA.
Anjana MohanDepartment of Pharmaceutical Outcomes and Policy, University of Houston College of Pharmacy, Houston, TX, USA.
Daniel MoussaDepartment of Pharmacy Practice and Translational Research, University of Houston, College of Pharmacy, Health 2, 4349 Martin Luther King Blvd, Houston, TX, 77204-5000, USA.
Susan AbughoshDepartment of Pharmaceutical Outcomes and Policy, University of Houston College of Pharmacy, Houston, TX, USA.
Meghana V TrivediDepartment of Pharmacy Practice and Translational Research, University of Houston, College of Pharmacy, Health 2, 4349 Martin Luther King Blvd, Houston, TX, 77204-5000, USA. mtrivedi@central.uh.edu.ORCID http://orcid.org/0000-0002-0585-5580
University of Houston · US

Funding

Testing a Digital Therapeutic for Smoking Cessation among Hispanic Persons who SmokeU54MD015946 · NIMHD · UNIVERSITY OF HOUSTON · PI MICHAEL J. ZVOLENSKY · 2020 to 2026
$22.0M
FOXA1 inhibitors to overcome endocrine resistance in ER+ breast cancerP20CA221729 · NCI · BAYLOR COLLEGE OF MEDICINE · PI CHOW, DIANA S-L., MATZUK, MARTIN M. · 2018 to 2021
$1.0M
NCI NIH HHS P20 CA221729NIMHD NIH HHS U54 MD015946NIMHD NIH HHS U54MD015946
6 · The paper itself

Abstract

backgroundAdherence to oral endocrine therapy (OET) is crucial in ensuring its maximum benefit in the prevention and treatment of hormone receptor-positive (HR +) breast cancer (BC). Medication use behavior is suboptimal especially in racial/ethnic minorities with lower socioeconomic status (SES).

aimWe aimed to assess the impact of the coronavirus disease 2019 (COVID-19) pandemic on OET adherence and identify demographic and/or clinical characteristics associated with nonadherence in racial/ethnic minorities with lower SES.

methodA retrospective study was conducted at the Harris Health System in Houston, Texas. Data were collected during the 6 months before and 6 months after the start of the pandemic. The adherence was assessed using the prescription refill data using the proportion of days covered. A multivariable logistic regression model was used to identify demographic/clinical characteristics associated with nonadherence. Eighteen years or older patients on appropriate doses of OET for prevention or treatment of BC were included.

resultsIn 258 patients, adherence was significantly lower during the pandemic (44%) compared to before the pandemic (57%). The demographic/clinical characteristics associated with OET nonadherence before the pandemic were Black/African American, obesity/extreme obesity, prevention setting, tamoxifen therapy, and 4 or more years on OET. During the pandemic, prevention setting and those not using home delivery were more likely to be nonadherent.

conclusionOET adherence was significantly reduced during the COVID-19 pandemic in racial/ethnic minority patients with low SES. Patient-centered interventions are necessary to improve OET adherence in these patients.

Indexed as

Breast NeoplasmsCOVID-19Ethnic and Racial MinoritiesEthnicityFemaleHumansLow Socioeconomic StatusMedication AdherenceMinority GroupsObesityPandemicsRetrospective StudiesAromatase inhibitorBreast cancerCOVID-19 pandemicMedication adherenceRacial and ethnic minorityTamoxifen

Identifiers

PMID37380914
PMCPMC10682303
OpenAlexW4382393952

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.