Evidence map›Paper›PMID 37380901›Full record

ArticleClinical neuroradiology2023

Treatment of Intracranial Vertebral Artery Dissecting Aneurysms Using Pipeline Embolization Devices : A Multicenter Cohort Study.

Ying Zhang, Fujunhui Zhang, Mirzat Turhon, Jiliang Huang, Mengxing Li, Qichen Peng, Zhaoxu Zheng, Jian Liu, Yisen Zhang, Jianmin Liu and 12 more

Registry-linked trialAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Clinical neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03831672 (Post Market Multi-Center Retrospective Research on Embolization of Intracranial Aneurysms With Pipeline Embolization Device in China), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03831672 unknown statusnot on this map

Post Market Multi-Center Retrospective Research on Embolization of Intracranial Aneurysms With Pipeline Embolization Device in China (PLUS)

TypeobservationalSponsorBeijing Neurosurgical InstituteRan2018 to 2019Enrolled200ConditionsIntracranial Aneurysm, Pipeline Embolization Device
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Ying ZhangDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China. yingzhang829@163.com.ORCID http://orcid.org/0000-0002-5812-372X
Fujunhui ZhangDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Mirzat TurhonDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Jiliang HuangDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Mengxing LiDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Qichen PengDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Zhaoxu ZhengDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Jian LiuDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Yisen ZhangDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Jianmin LiuChanghai Hospital Affiliated to Naval Medical University, Shanghai, China.
Hongqi ZhangXuanwu Hospital, Capital Medical University, Beijing, China.
Tianxiao LiZhengzhou University People's Hospital, Zhengzhou, China.
Donglei SongShanghai Donglei Brain Hospital, Shanghai, China.
Yuanli ZhaoPeking University International Hospital, Beijing, China.
Maimaitili AishaFirst Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Yunyan WangQilu Hospital of Shandong University, Jinan, China.
Wenfeng FengNanfang Hospital, Southern Medical University, Guangzhou, China.
Yang WangBeijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Jieqing WanRenji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Guohua MaoSecond Affiliated Hospital of Nanchang University, Nanchang, China.
Huaizhang ShiFirst Affiliated Hospital of Harbin Medical University, Harbin, China.
Sheng GuanFirst Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Funding

Capital's Funds for Health Improvement and Research 2022-01-2041National Natural Science Foundation of China 82072036National Natural Science Foundation of China 82272092Research Projects of National Health Commission Capacity Building and Continuing Education Center in 2021 GWJJ2021100103Summit Talent Program DFL20220504
6 · The paper itself

Abstract

purposeIntracranial vertebral artery dissecting aneurysm (IVADA) is a rare type of aneurysm with high morbidity and mortality. Recently, the application of pipeline embolization devices (PEDs) has been extended to IVADAs. Here, we aim to investigate the safety and effectiveness of PEDs for IVADAs.

methodWe retrospectively reviewed the PLUS database to identify patients who had IVADAs and were treated with PEDs from 2014 to 2019 at 14 centers across China. Data including patient and aneurysm characteristics, procedure details, angiographic and clinical results, relationship with the ipsilateral posterior inferior cerebellar artery (PICA), and patency of the PICA following PED coverage were analyzed.

resultsIn this study 52 consecutive patients with 52 IVADAs were included. The mean age was 52.33 years and 82.7% were male. With a median follow-up of 10.5 months, the complete occlusion rate was 93.8% (45/48) and no recurrence or in-stent stenosis was detected. The total postoperative complication rate and mortality were 11.5% and 1.9%, respectively. Complications occurred in 9.6% (5/52) of patients within 30 days after the operation, including ischemic stroke in 3 and hemorrhagic stroke in 2. Another patient suffered an ischemic stroke at follow-up, 78.8% (41/52) PICAs were covered by PEDs, 1 case (2.4%) had a functional disability due to PICA occlusion, while 39.0% (16/41) had reduced flow during follow-up but hardly caused any obvious neurological deficits. Patients with IVADA involving PICA had a trend towards more complications (66.7% vs. 51.1%; P = 1).

conclusionTreating IVADAs with PEDs may be a safe and effective option, with favorable clinical and angiographic outcomes; however, complications associated with this treatment should not be ignored. REGISTRATION: http://www. CLINICALTRIALS: gov . Unique identifier: NCT03831672.

Indexed as

Aortic DissectionEmbolization, TherapeuticIntracranial AneurysmIschemic StrokeVertebral Artery DissectionCerebral AngiographyFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeVertebral ArteryComplicationsDissecting aneurysmFlow diverterPosterior inferior cerebellar arteryVertebral artery

Identifiers

PMID37380901

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.