Evidence map›Paper›PMID 37380775›Full record

ArticleNature2023

BTN3A3 evasion promotes the zoonotic potential of influenza A viruses.

Rute Maria Pinto, Siddharth Bakshi, Spyros Lytras, Mohammad Khalid Zakaria, Simon Swingler, Julie C Worrell, Vanessa Herder, Kerrie E Hargrave, Margus Varjak, Natalia Cameron-Ruiz and 23 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 1 pooled it
19.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Avian influenza overview June-August 2026.EFSA journal. European Food Safety Authority · 2026
    Article
  5. Article
  6. Influenza.Nature reviews. Disease primers · 2026
    Review
  7. Article
  8. Article
  9. Avian influenza overview March-May 2026.EFSA journal. European Food Safety Authority · 2026
    Article
  10. Article
  11. Imported case of avian influenza A(H9N2) virus infection in a patient with miliary tuberculosis, Italy, March 2026.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  12. Article
  13. Avian influenza overview December 2025-February 2026.EFSA journal. European Food Safety Authority · 2026
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

33 authors at 5 institutions in 4 countries.

Rute Maria PintoMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
Siddharth Bakshi *MRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
Spyros Lytras *MRC-University of Glasgow Centre for Virus Research, Glasgow, UK.ORCID 0000-0003-4202-6682
Mohammad Khalid Zakaria *MRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
Simon SwinglerMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
Julie C WorrellSchool of Infection and Immunity, University of Glasgow, Glasgow, UK.ORCID 0000-0001-7754-1364
Vanessa HerderMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
Kerrie E HargraveSchool of Infection and Immunity, University of Glasgow, Glasgow, UK.
Margus VarjakMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
Natalia Cameron-RuizMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
Mila Collados RodriguezMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
Mariana VarelaMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
Arthur WickenhagenMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
Colin LoneyMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
Yanlong PeiDepartment of Pathobiology, University of Guelph, Guelph, Ontario, Canada.
Joseph HughesMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.ORCID 0000-0003-2556-2563
Elise ValetteMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
Matthew L TurnbullMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.ORCID 0000-0002-7234-5871
Wilhelm FurnonMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.ORCID 0000-0002-5588-4232
Quan GuMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.ORCID 0000-0002-1201-6734
Lauren OrrMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.ORCID 0000-0002-4553-3703
Aislynn TaggartMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
Ola DieboldThe Roslin Institute, University of Edinburgh, Edinburgh, UK.
Chris DavisMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.ORCID 0000-0002-7317-3266
Chris BoutellMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.ORCID 0000-0002-2970-7785
Finn GreyThe Roslin Institute, University of Edinburgh, Edinburgh, UK.
Edward HutchinsonMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
Paul DigardThe Roslin Institute, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-0872-9440
Isabella MonneIstituto Zooprofilattico Sperimentale delle Venezie (IZSVe), Legnaro, Italy.
Sarah K WoottonDepartment of Pathobiology, University of Guelph, Guelph, Ontario, Canada.ORCID 0000-0002-5985-2406
Megan K L MacLeodSchool of Infection and Immunity, University of Glasgow, Glasgow, UK.
Sam J WilsonMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.ORCID 0000-0002-6065-0895
Massimo PalmariniMRC-University of Glasgow Centre for Virus Research, Glasgow, UK. massimo.palmarini@glasgow.ac.uk.ORCID 0000-0001-7007-4070
MRC University of Glasgow Centre for Virus Research · GBRoslin Institute · GBUniversity of Glasgow · GBUniversity of Guelph · CAIstituto Zooprofilattico Sperimentale delle Venezie · IT

Funding

Medical Research Council MC_UU_00034/2Medical Research Council MC_UU_00034/3Medical Research Council MC_UU_00034/5Medical Research Council MC_UU_00034/8Medical Research Council MC_UU_12014/10Medical Research Council MC_UU_12014/12Medical Research Council MC_UU_12014/5Medical Research Council MC_UU_12014/9Medical Research Council MC_UU_12016/10Medical Research Council MR/K024752/1Medical Research Council MR/N008618/1Medical Research Council MR/P022642/1Medical Research Council MR/T029188/1Medical Research Council MR/V01157X/1Medical Research Council MR/V035789/1Wellcome Trust 206369/Z/17/ZWellcome Trust 210703/Z/18/Z
6 · The paper itself

Abstract

Spillover events of avian influenza A viruses (IAVs) to humans could represent the first step in a future pandemic

Indexed as

BirdsHost Microbial InteractionsInfluenza A virusInfluenza, HumanInfluenza in BirdsViral ZoonosesAnimalsHumansNuclear ProteinsNucleocapsid ProteinsPrimatesRespiratory SystemRisk AssessmentTranscription FactorsVirus ReplicationNP protein, Influenza A virusNuclear ProteinsNucleocapsid Proteinstranscription factor BTF3Transcription Factors

Identifiers

PMID37380775
OpenAlexW4382394371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.