Evidence map›Paper›PMID 37380765›Full record

ArticleNature2023

Circuit coordination of opposing neuropeptide and neurotransmitter signals.

Marta E Soden, Joshua X Yee, Larry S Zweifel

Open access · greenAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
8.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Nucleus of the solitary tract regulation of cue-induced appetitive behaviors via midbrain dopamine neurons.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Robust PHP in Adult Hippocampus: Essential Assay Optimizations.bioRxiv : the preprint server for biology · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Genes & development · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marta E SodenDepartment of Pharmacology, University of Washington, Seattle, WA, USA. msoden@uw.edu.ORCID 0000-0002-0695-8653
Joshua X YeeDepartment of Pharmacology, University of Washington, Seattle, WA, USA.ORCID 0000-0002-3661-2071
Larry S ZweifelDepartment of Pharmacology, University of Washington, Seattle, WA, USA. larryz@uw.edu.ORCID 0000-0003-3465-5331
University of Washington · US

Funding

University of Washington Center of Excellence in Opioid Addiction ResearchP30DA048736 · NIDA · UNIVERSITY OF WASHINGTON · PI Charles Chavkin · 2019 to 2026
$13.0M
Isolation of brain reward circuits using peptidergic systemsR01DA044315 · NIDA · UNIVERSITY OF WASHINGTON · PI LARRY S ZWEIFEL · 2018 to 2026
$3.5M
Differential modulation of dopamine neurons by distinct neurotensin inputsR01DA054924 · NIDA · UNIVERSITY OF WASHINGTON · PI Marta E Soden · 2022 to 2026
$1.8M
Innovation of methods for in vivo monitoring and manipulation of neurotensin circuitsR21MH121774 · NIMH · UNIVERSITY OF WASHINGTON · PI SODEN, MARTA E · 2020 to 2021
$428k
NIDA NIH HHS P30 DA048736NIDA NIH HHS R01 DA044315NIDA NIH HHS R01 DA054924NIMH NIH HHS R21 MH121774
6 · The paper itself

Abstract

Fast-acting neurotransmitters and slow, modulatory neuropeptides are co-released from neurons in the central nervous system, albeit from distinct synaptic vesicles

Indexed as

BrainNeural PathwaysNeurotensinNeurotransmitter AgentsSignal TransductionCalciumCRISPR-Cas SystemsDopamineDopaminergic NeuronsGABAergic Neuronsgamma-Aminobutyric AcidGene EditingHypothalamic Area, LateralReceptors, NeurotensinVentral Tegmental AreaCalciumDopaminegamma-Aminobutyric AcidNeurotensinNeurotransmitter AgentsReceptors, Neurotensin

Identifiers

PMID37380765
PMCPMC10947507
OpenAlexW4382394370

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.