Evidence map›Paper›PMID 37380758›Full record

ArticleSpinal cord2023

D-dimer/fibrinogen ratio for the prediction of deep venous thrombosis after traumatic spinal cord injury.

Changyi Wang, Xi Yu, Tiantian Wang, Mingfu Ding, Liyu Ran

Abstract read
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In one paragraph

Article in Spinal cord, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Changyi WangDepartment of Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China. changyi11@scu.edu.cn.ORCID http://orcid.org/0000-0003-3153-9458
Xi YuDepartment of Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Tiantian WangKey Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Mingfu DingDepartment of Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Liyu RanDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Sichuan University · CN

Funding

China Postdoctoral Science Foundation 2021M692299China Postdoctoral Science Foundation 2022T150452National Natural Science Foundation of China (National Science Foundation of China) 82102656
6 · The paper itself

Abstract

STUDY

designRetrospective cohort study.

objectivesTo evaluate the predictive value of D-dimer/fibrinogen (D/F) ratio for deep vein thrombosis (DVT) in patients with traumatic spinal cord injury (SCI).

settingDepartment of Rehabilitation Medicine Center, West China Hospital, Sichuan University.

methodsSCI patients within 24 h of trauma were consecutively enrolled. DVT was diagnosed by DUS examination during hospitalization. Multivariable logistic regression analysis was performed to determine the relationship between D/F ratio and DVT. Stratified logistic regression analysis was performed to identify effect modifiers. The receiver operating characteristic (ROC) curve was conducted to assess the predictive value of D/F ratio.

resultsA total of 284 patients with SCI were included, of whom 106 (37.3%) developed DVT. D/F ratio was positively correlated with DVT (OR 1.17, 95% confidence interval [CI] 1.04-1.31, p = 0.009). Patients in the upper D/F ratio tertile (3.15-18.27) had a higher risk of DVT than patients in the lower tertile (0.08-0.97) after adjustment for potential confounders (OR 6.01, 95% CI 2.24-16.15, p < 0.001). The risk of DVT increased stepwise across D/F ratio tertiles (p for trend = 0.003). The area under the ROC curve (AUC) was 0.758 (95% CI 0.704-0.806). There was a significant interaction between D/F ratio and neurological level of injury (p for interaction = 0.003) and the association between D/F ratio and DVT remained significant only in patients with cervical injury.

conclusionsA higher D/F ratio was independently associated with a higher risk of DVT in a dose-dependent manner in patients with cervical SCI.

Indexed as

Spinal Cord InjuriesVenous ThrombosisFibrin Fibrinogen Degradation ProductsHumansRetrospective StudiesRisk FactorsFibrin Fibrinogen Degradation Productsfibrin fragment D

Identifiers

PMID37380758
OpenAlexW4382400258

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.