Evidence map›Paper›PMID 37380750›Full record

ReviewNature biomedical engineering2023

Algorithmic fairness in artificial intelligence for medicine and healthcare.

Richard J Chen, Judy J Wang, Drew F K Williamson, Tiffany Y Chen, Jana Lipkova, Ming Y Lu, Sharifa Sahai, Faisal Mahmood

Abstract readReview
In one paragraph

Review in Nature biomedical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 316 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
316citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

316 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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256 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Richard J ChenDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-0389-1331
Judy J WangDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-4905-6593
Drew F K WilliamsonDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-1745-8846
Tiffany Y ChenDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-2546-2941
Jana LipkovaDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-8101-4794
Ming Y LuDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-0009-9699
Sharifa SahaiDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Faisal MahmoodDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. FaisalMahmood@bwh.harvard.edu.ORCID 0000-0001-7587-1562

Funding

Training Program in Bioinformatics and Integrative GenomicsT32HG002295 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Peter J Park · 2001 to 2026
$15.8M
Multimodal and Generative AI for PathologyR35GM138216 · NIGMS · BROAD INSTITUTE, INC. · PI Faisal Mahmood · 2020 to 2026
$3.4M
Oncopathology Training ProgramT32CA251062 · NCI · DANA-FARBER CANCER INST · PI JON C. ASTER, KATHLEEN H BURNS · 2020 to 2026
$2.4M
NCI NIH HHS T32 CA251062NHGRI NIH HHS T32 HG002295NIGMS NIH HHS R35 GM138216NIGMS NIH HHS R35GM138216
6 · The paper itself

Abstract

In healthcare, the development and deployment of insufficiently fair systems of artificial intelligence (AI) can undermine the delivery of equitable care. Assessments of AI models stratified across subpopulations have revealed inequalities in how patients are diagnosed, treated and billed. In this Perspective, we outline fairness in machine learning through the lens of healthcare, and discuss how algorithmic biases (in data acquisition, genetic variation and intra-observer labelling variability, in particular) arise in clinical workflows and the resulting healthcare disparities. We also review emerging technology for mitigating biases via disentanglement, federated learning and model explainability, and their role in the development of AI-based software as a medical device.

Indexed as

Artificial IntelligenceMedicineDelivery of Health CareHumansMachine LearningSoftware

Identifiers

PMID37380750
PMCPMC10632090

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.