ArticleScientific reports2023
iMPI: portable human-sized magnetic particle imaging scanner for real-time endovascular interventions.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 58 citations in OpenAlex.
- Verification and validation in canine cadaver of an MPI-integrable RF head coil for magnetic particle hyperthermia.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2026Article
- Towards robot-assisted magnetic particle imaging for mobile point-of-care (neuro)vascular applications.Scientific reports · 2026Article
- Whole-body in vivo MPI cytometry reveals injection route-, dose-, cell size-, and disease-dependent differences in organ distribution.Science advances · 2026Article
- Imaging of Artificial Tumor Models in an Anatomical Breast Phantom with a Single-Sided Magnetic Particle Imaging Scanner.Tomography (Ann Arbor, Mich.) · 2026Article
- Magnetic Particle Imaging in Human Subjects.Research square · 2026Article
- Toward high-stability quantitative carriers: development of superparamagnetic nanocarriers and a high-sensitivity mixing-frequency narrow-band magnetic particle imaging detection system.Frontiers in pharmacology · 2026Article
- Continuous Coagulation Monitoring in Human Blood Samples via Magnetic Particle Spectroscopy.International journal of nanomedicine · 2026Article
- Superparamagnetic iron oxide nanoparticles in clinical applications: current status and future perspectives.EBioMedicine · 2025Review
- Towards clinical magnetic particle imaging: safety measurements of medical implants in a human cadaver model.Communications engineering · 2025Article
- Superferromagnetic Disk Particles for Magnetic Particle Imaging.Small methods · 2025Article
- Enhanced performance of a single-sided MPI scanner with a hybrid surface-volume excitation coil.Physics in medicine and biology · 2025Article
- Cardiovascular Imaging Applications, Implementations, and Challenges Using Novel Magnetic Particle Imaging.Bioengineering (Basel, Switzerland) · 2025Review
- Therapeutic mRNA vaccine applications in oncology.Molecular therapy : the journal of the American Society of Gene Therapy · 2025Review
- Optical-magnetic Imaging for Optimizing Lymphodepletion-TIL Combination Therapy in Breast Cancer.Molecular imaging and biology · 2025Article
- Development and Degradation Study of PLA-Based Medical Implant Markers for Magnetic Particle Imaging.Macromolecular bioscience · 2025Article
- Magnetic particle imaging angiography of the femoral artery in a human cadaveric perfusion model.Communications medicine · 2025Article
- Non-FFP-Based Magnetic Particle Imaging (NFMPI) with an Open-Type RF Coil System: A Feasibility Study.Sensors (Basel, Switzerland) · 2025Article
- Design, construction and validation of a magnetic particle imaging (MPI) system for human brain imaging.Physics in medicine and biology · 2025Article
- Machine Learning and Deep Learning Applications in Magnetic Particle Imaging.Journal of magnetic resonance imaging : JMRI · 2025Review
- Tomographic Magnetic Particle Imaging With a Single-Sided Field-Free Line Scanner.IEEE transactions on bio-medical engineering · 2024Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Minimally invasive endovascular interventions have become an important tool for the treatment of cardiovascular diseases such as ischemic heart disease, peripheral artery disease, and stroke. X-ray fluoroscopy and digital subtraction angiography are used to precisely guide these procedures, but they are associated with radiation exposure for patients and clinical staff. Magnetic Particle Imaging (MPI) is an emerging imaging technology using time-varying magnetic fields combined with magnetic nanoparticle tracers for fast and highly sensitive imaging. In recent years, basic experiments have shown that MPI has great potential for cardiovascular applications. However, commercially available MPI scanners were too large and expensive and had a small field of view (FOV) designed for rodents, which limited further translational research. The first human-sized MPI scanner designed specifically for brain imaging showed promising results but had limitations in gradient strength, acquisition time and portability. Here, we present a portable interventional MPI (iMPI) system dedicated for real-time endovascular interventions free of ionizing radiation. It uses a novel field generator approach with a very large FOV and an application-oriented open design enabling hybrid approaches with conventional X-ray-based angiography. The feasibility of a real-time iMPI-guided percutaneous transluminal angioplasty (PTA) is shown in a realistic dynamic human-sized leg model.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.