Evidence map›Paper›PMID 37380650›Full record

ArticleNature communications2023

Using mortuary and burial data to place COVID-19 in Lusaka, Zambia within a global context.

Richard J Sheppard, Oliver J Watson, Rachel Pieciak, James Lungu, Geoffrey Kwenda, Crispin Moyo, Stephen Longa Chanda, Gregory Barnsley, Nicholas F Brazeau, Ines C G Gerard-Ursin and 13 more

Erratum issuedAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors.

Richard J SheppardMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK.
Oliver J WatsonMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK.ORCID http://orcid.org/0000-0003-2374-0741
Rachel PieciakDepartment of Global Health, Boston University School of Public Health, Boston, MA, USA.
James LunguAvencion Limited, Lusaka, Zambia.
Geoffrey KwendaDepartment of Biomedical Sciences, School of Health Sciences, University of Zambia, Lusaka, Zambia.
Crispin MoyoAvencion Limited, Lusaka, Zambia.
Stephen Longa ChandaZambia National Public Health Institute, Lusaka, Zambia.ORCID http://orcid.org/0000-0002-4326-8571
Gregory BarnsleyMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK.ORCID http://orcid.org/0000-0001-7972-0737
Nicholas F BrazeauMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK.
Ines C G Gerard-UrsinMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK.
Daniela Olivera MesaMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK.ORCID http://orcid.org/0000-0002-6190-2855
Charles WhittakerMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK.ORCID http://orcid.org/0000-0002-5003-2575
Simon GregsonMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK.
Lucy C OkellMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK.ORCID http://orcid.org/0000-0001-7202-6873
Azra C GhaniMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK.ORCID http://orcid.org/0000-0002-0007-4910
William B MacLeodDepartment of Global Health, Boston University School of Public Health, Boston, MA, USA.
Emanuele Del FavaCarlo F. Dondena Centre for Research on Social Dynamics and Public Policy, Bocconi University, Milan, Italy.ORCID http://orcid.org/0000-0001-7352-8525
Alessia MelegaroCarlo F. Dondena Centre for Research on Social Dynamics and Public Policy, Bocconi University, Milan, Italy.ORCID http://orcid.org/0000-0003-2221-8898
Jonas Z HinesCenters for Disease Control and Prevention, Lusaka, Zambia.
Lloyd B MulengaZambia Ministry of Health, Lusaka, Zambia.
Patrick G T Walker *MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK. patrick.walker06@imperial.ac.uk.
Lawrence Mwananyanda *Department of Global Health, Boston University School of Public Health, Boston, MA, USA.
Christopher J Gill *Department of Global Health, Boston University School of Public Health, Boston, MA, USA.

Funding

Academy of Medical Sciences SBF005\1107CGH CDC HHS U01 GH002319Medical Research Council MR/R015600/1PEPFARWellcome TrustWellcome Trust 221350/Z/20/ZWellcome Trust 224190/Z/21/Z
6 · The paper itself

Abstract

Reported COVID-19 cases and associated mortality remain low in many sub-Saharan countries relative to global averages, but true impact is difficult to estimate given limitations around surveillance and mortality registration. In Lusaka, Zambia, burial registration and SARS-CoV-2 prevalence data during 2020 allow estimation of excess mortality and transmission. Relative to pre-pandemic patterns, we estimate age-dependent mortality increases, totalling 3212 excess deaths (95% CrI: 2104-4591), representing an 18.5% (95% CrI: 13.0-25.2%) increase relative to pre-pandemic levels. Using a dynamical model-based inferential framework, we find that these mortality patterns and SARS-CoV-2 prevalence data are in agreement with established COVID-19 severity estimates. Our results support hypotheses that COVID-19 impact in Lusaka during 2020 was consistent with COVID-19 epidemics elsewhere, without requiring exceptional explanations for low reported figures. For more equitable decision-making during future pandemics, barriers to ascertaining attributable mortality in low-income settings must be addressed and factored into discourse around reported impact differences.

Indexed as

COVID-19BurialHumansPandemicsSARS-CoV-2Zambia

Identifiers

PMID37380650
PMCPMC10307769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.