Evidence map›Paper›PMID 37380607›Full record

ReviewChemMedChem2023

Peptide Assemblies for Cancer Therapy.

Yuchen Qiao, Bing Xu

Abstract readReview
In one paragraph

Review in ChemMedChem, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Supramolecular Behaviour of Heterochiral Dipeptides With Ile.Journal of peptide science : an official publication of the European Peptide Society · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yuchen QiaoDepartment of Chemistry, Brandeis University, 415 South Street, Waltham, MA 02454, USA.ORCID 0009-0008-6401-6980
Bing XuDepartment of Chemistry, Brandeis University, 415 South Street, Waltham, MA 02454, USA.ORCID 0000-0002-4639-387X

Funding

Subcellular Enzyme-instructed self-assembly for molecular anticancer nanomedicinesR01CA142746 · NCI · BRANDEIS UNIVERSITY · PI Bing Xu · 2010 to 2026
$6.4M
Testing in-situ formed nanofibers for inhibiting metastatic osteosarcoma (mOS) in murine modelsR03CA262920 · NCI · BRANDEIS UNIVERSITY · PI XU, BING · 2021 to 2022
$163k
NCI NIH HHS R01 CA142746NCI NIH HHS R03 CA262920NIH HHS CA142746NIH HHS CA262920
6 · The paper itself

Abstract

Supramolecular assemblies made by the self-assembly of peptides are finding an increasing number of applications in various fields. While the early exploration of peptide assemblies centered on tissue engineering or regenerative medicine, the recent development has shown that peptide assemblies can act as supramolecular medicine for cancer therapy. This review covers the progress of applying peptide assemblies for cancer therapy, with the emphasis on the works appeared over the last five years. We start with the introduction of a few seminal works on peptide assemblies, then discuss the combination of peptide assemblies with anticancer drugs. Next, we highlight the use of enzyme-controlled transformation or shapeshifting of peptide assemblies for inhibiting cancer cells and tumors. After that, we provide the outlook for this exciting field that promises new kind of therapeutics for cancer therapy.

Indexed as

Antineoplastic AgentsNeoplasmsHumansPeptidesTissue EngineeringAntineoplastic AgentsPeptidescancer therapyenzymepeptideself-assemblysupramolecular medicine

Identifiers

PMID37380607
PMCPMC10613339

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.