Evidence map›Paper›PMID 37380561›Full record

ArticleZeitschrift fur medizinische Physik2025

Silicone phantoms fabricated with multi-material extrusion 3D printing technology mimicking imaging properties of soft tissues in CT.

Sepideh Hatamikia, Laszlo Jaksa, Gernot Kronreif, Wolfgang Birkfellner, Joachim Kettenbach, Martin Buschmann, Andrea Lorenz

Abstract read
In one paragraph

Article in Zeitschrift fur medizinische Physik, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sepideh HatamikiaAustrian Center for Medical Innovation and Technology (ACMIT), Wiener Neustadt, Austria; Research Center for Medical Image Analysis and Artificial Intelligence (MIAAI), Department of Medicine, Danube Private University, Krems, Austria. Electronic address: sepideh.hatamikia@acmit.at.
Laszlo JaksaAustrian Center for Medical Innovation and Technology (ACMIT), Wiener Neustadt, Austria.
Gernot KronreifAustrian Center for Medical Innovation and Technology (ACMIT), Wiener Neustadt, Austria.
Wolfgang BirkfellnerCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Joachim KettenbachInstitute of Diagnostic, Interventional Radiology and Nuclear Medicine, Landesklinikum Wiener Neustadt, Wiener Neustadt, Austria.
Martin BuschmannDepartment of Radiation Oncology, Medical University of Vienna/AKH Wien, Vienna, Austria.
Andrea LorenzAustrian Center for Medical Innovation and Technology (ACMIT), Wiener Neustadt, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, 3D printing has been widely used to fabricate medical imaging phantoms. So far, various rigid 3D printable materials have been investigated for their radiological properties and efficiency in imaging phantom fabrication. However, flexible, soft tissue materials are also needed for imaging phantoms for simulating several clinical scenarios where anatomical deformations is important. Recently, various additive manufacturing technologies have been used to produce anatomical models based on extrusion techniques that allow the fabrication of soft tissue materials. To date, there is no systematic study in the literature investigating the radiological properties of silicone rubber materials/fluids for imaging phantoms fabricated directly by extrusion using 3D printing techniques. The aim of this study was to investigate the radiological properties of 3D printed phantoms made of silicone in CT imaging. To achieve this goal, the radiodensity as described as Hounsfield Units (HUs) of several samples composed of three different silicone printing materials were evaluated by changing the infill density to adjust their radiological properties. A comparison of HU values with a Gammex Tissue Characterization Phantom was performed. In addition, a reproducibility analysis was performed by creating several replicas for specific infill densities. A scaled down anatomical model derived from an abdominal CT was also fabricated and the resulting HU values were evaluated. For the three different silicone materials, a spectrum ranging from -639 to +780 HU was obtained on CT at a scan setting of 120 kVp. In addition, using different infill densities, the printed materials were able to achieve a similar radiodensity range as obtained in different tissue-equivalent inserts in the Gammex phantom (238 HU to -673 HU). The reproducibility results showed good agreement between the HU values of the replicas compared to the original samples, confirming the reproducibility of the printed materials. A good agreement was observed between the HU target values in abdominal CT and the HU values of the 3D-printed anatomical phantom in all tissues.

Indexed as

Phantoms, ImagingPrinting, Three-DimensionalSiliconesTomography, X-Ray ComputedHumansModels, AnatomicReproducibility of ResultsSilicones3D printingCT imagingRadiological propertiesSilicone materials

Identifiers

PMID37380561
PMCPMC12166924

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.