Evidence map›Paper›PMID 37380391›Full record

ArticleSheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi2023

[Animal experimental study on the effects of different levels of amputation on cardiovascular system].

Lei Min, Wentao Jiang, Zhongyou Li, Xiao Li, Junjie Diao, Renjing Liu, Tianxiang Tai, Taoping Bai

Open access · greenAbstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lei MinDepartment of Mechanics & Engineering, College of Architecture and Environment, Sichuan University, Chengdu 610065, P.R.China.
Wentao JiangDepartment of Mechanics & Engineering, College of Architecture and Environment, Sichuan University, Chengdu 610065, P.R.China.
Zhongyou LiDepartment of Mechanics & Engineering, College of Architecture and Environment, Sichuan University, Chengdu 610065, P.R.China.
Xiao LiDepartment of Mechanics & Engineering, College of Architecture and Environment, Sichuan University, Chengdu 610065, P.R.China.
Junjie DiaoDepartment of Mechanics & Engineering, College of Architecture and Environment, Sichuan University, Chengdu 610065, P.R.China.
Renjing LiuDepartment of Mechanics & Engineering, College of Architecture and Environment, Sichuan University, Chengdu 610065, P.R.China.
Tianxiang TaiDepartment of Mechanics & Engineering, College of Architecture and Environment, Sichuan University, Chengdu 610065, P.R.China.
Taoping BaiDepartment of Mechanics & Engineering, College of Architecture and Environment, Sichuan University, Chengdu 610065, P.R.China.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular injury resulting from lower limb amputation leads to the redistribution of blood flow and changes in vascular terminal resistance, which can affect the cardiovascular system. However, there was no clear understanding of how different amputation levels affect the cardiovascular system in animal experiments. Therefore, this study established two animal models of above-knee amputation (AKA) and below-knee amputation (BKA) to explore the effects of different amputation levels on the cardiovascular system through blood and histopathological examinations. The results showed that amputation caused pathological changes in the cardiovascular system of animals, including endothelial injury, inflammation, and angiosclerosis. The degree of cardiovascular injury was higher in the AKA group than in the BKA group. This study sheds light on the internal mechanisms of amputation's impact on the cardiovascular system. Based on the amputation level of patients, the findings recommend more comprehensive and targeted monitoring after surgery and necessary interventions to prevent cardiovascular diseases.

Indexed as

Animal ExperimentationCardiovascular DiseasesCardiovascular SystemHypertensionAmputation, SurgicalAnimalsAmputation levelsAnimal modelBiochemical indexCardiovascular systemPathological examination

Identifiers

PMID37380391
PMCPMC10307619
OpenAlexW4382502808

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.