Evidence map›Paper›PMID 37379458›Full record

ArticleACS chemical biology2023

Revealing Drivers for Carboxy-

Christian E Loo, Mark A Hix, Tong Wang, G Andrés Cisneros, Rahul M Kohli

Open access · greenAbstract read
In one paragraph

Article in ACS chemical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. When theory came first: a review of theoretical chemical predictions ahead of experiments.Pure and applied chemistry. Chimie pure et appliquee · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Christian E LooGraduate Group in Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Mark A HixDepartment of Chemistry, Wayne State University, Detroit, Michigan 48202, United States.
Tong WangGraduate Group in Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
G Andrés CisnerosDepartment of Physics, University of Texas at Dallas, Richardson, Texas 75801, United States.ORCID 0000-0001-6629-3430
Rahul M KohliDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.ORCID 0000-0002-7689-5678
University of Pennsylvania · USThe University of Texas at Dallas · USWayne State University · US

Funding

Ultra low-input epigenetic sequencing with combined enzymatic and long-read technologiesR01HG010646 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI Gang Fang, Rahul Manu Kohli · 2019 to 2026
$3.9M
Theory and Simulation of DNA Repair Enzymes; Mechanism, Structure and FunctionR01GM108583 · NIGMS · WAYNE STATE UNIVERSITY · PI CISNEROS, GERARDO ANDRES · 2014 to 2022
$2.9M
Advancing Epigenetic Sequencing Through Solid-Phase Enzymatic ApproachesF31HG012892 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI LOO, CHRISTIAN ETHAN · 2023 to 2024
$95k
NHGRI NIH HHS F31 HG012892NHGRI NIH HHS R01 HG010646NIGMS NIH HHS R01 GM108583
6 · The paper itself

Abstract

Methylation of DNA plays a key role in diverse biological processes spanning from bacteria to mammals. DNA methyltransferases (MTases) typically employ

Indexed as

CytosineMethyltransferasesS-AdenosylmethionineAnimalsDNADNA MethylationDNA Modification MethylasesMammals5-carboxymethylcytosineCytosineDNADNA Modification MethylasesMethyltransferasesS-Adenosylmethionine

Identifiers

PMID37379458
PMCPMC10592258
OpenAlexW4382363116

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.