Evidence map›Paper›PMID 37379338›Full record

ArticlePLoS neglected tropical diseases2023

Diagnostic capacities and treatment practices on implantation mycoses: Results from the 2022 WHO global online survey.

Barbara Milani, Daniel Argaw Dagne, Hye Lynn Choi, Marco Schito, Heather Anne Stone

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Establishment of epidemiological cutoff values againstJournal of clinical microbiology · 2026
    Article
  2. Mycetoma.PLoS neglected tropical diseases · 2026
    Review
  3. Article
  4. Sandalwood Sesquiterpene (Molecules (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Chromoblastomycosis: a case series from Sumba, eastern Indonesia.Clinical and experimental dermatology · 2025
    Article
  7. Review
  8. Mycetoma in Somalia: an updated literature review.Annals of medicine and surgery (2012) · 2025
    Review
  9. Towards enhanced control of mycetoma: a roadmap to achieve the UN's sustainable development goals by 2030.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2024
    Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Barbara MilaniWHO consultant, World Health Organization, Geneva, Switzeland.ORCID 0000-0002-1145-4628
Daniel Argaw DagneDepartment of Control of Neglected Tropical Diseases [WHO/NTD], World Health Organization, Geneva, Switzeland.
Hye Lynn ChoiDepartment of Control of Neglected Tropical Diseases [WHO/NTD], World Health Organization, Geneva, Switzeland.
Marco SchitoCURE Drug Repurposing Collaboratory, Critical Path Institute, Tucson, Arizona, United States of America.
Heather Anne StoneOffice of Medical Policy, Center for Drug Evaluation and Research, United States Food and Drug Administration, Silver Spring, Maryland, United States of America.

Funding

Strengthen regulatory systems to ensure the safety and quality of food and medical products.U01FD006603 · FDA · WORLD HEALTH ORGANIZATION · PI SILLO, HIITI · 2018 to 2022
$3.7M
FDA HHS U01 FD006603World Health Organization 001
6 · The paper itself

Abstract

Between January and March 2022, WHO conducted a global online survey to collect data on diagnostic capacities and treatment practices in different settings for four implantation mycoses: eumycetoma, actinomycetoma, cutaneous sporotrichosis and chromoblastomycosis. The survey investigated the type of diagnostic methods available in countries at various health system levels (tertiary, secondary, primary level) and the medicines used to treat implantation mycoses, with a view to understanding the level of drug repurposing for treatment of these diseases. 142 respondents from 47 countries, including all continents, contributed data: 60% were from middle-income countries, with 59% working at the tertiary level of the health system and 30% at the secondary level. The results presented in this article provide information on the current diagnostic capacity and treatment trends for both pharmacological and non-pharmacological interventions. In addition, the survey provides insight on refractory case rates, as well as other challenges, such as availability and affordability of medicines, especially in middle-income countries. Although the study has limitations, the survey-collected data confirms that drug repurposing is occurring for all four surveyed implantation mycoses. The implementation of an openly accessible global and/or a national treatment registry for implantation mycoses could contribute to address the gaps in epidemiological information and collect valuable observational data to inform treatment guidelines and clinical research.

Indexed as

MycetomaMycosesSporotrichosisHumansSurveys and QuestionnairesWorld Health Organization

Identifiers

PMID37379338
PMCPMC10335693

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.