Evidence map›Paper›PMID 37379091›Full record

ArticleAnesthesia progress2023

The Physical Compatibility of Glycopyrrolate and Rocuronium.

Austen L Weeks, John Sotos, Bryce Woolsey, William M Johnston, Bryant W Cornelius

Open access · greenAbstract read
In one paragraph

Article in Anesthesia progress, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Austen L WeeksDentist Anesthesiologist, Graduate of The Ohio State University College of Dentistry Dental Anesthesiology Program, Class of 2021, Columbus, Ohio.
John SotosThe Ohio State University College of Dentistry, Columbus, Ohio.
Bryce WoolseyGeneral Practice Resident, The Ohio State University College of Dentistry, Columbus, Ohio.
William M JohnstonProfessor Emeritus, The Ohio State University College of Dentistry, Columbus, Ohio.
Bryant W CorneliusAssistant Professor and Program Director, of Dental Anesthesiology, The Ohio State University College of Dentistry, Columbus, Ohio.
The Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveScientific evidence has rarely, if at all, been reported in the literature demonstrating analytical confirmation of the physical compatibility and stability of glycopyrrolate and rocuronium combined. The purpose of this experiment was to determine if glycopyrrolate and rocuronium are physically compatible.

methodsGlycopyrrolate and rocuronium were combined in various containers, observed over a 60-minute period, and compared against positive and negative controls. Measured metrics included color change, precipitate formation, Tyndall beam test, turbidity, and pH. Statistical analyses were used to assess significance of data trends.

resultsThe combination of glycopyrrolate and rocuronium did not result in any color change, precipitate formation, a positive Tyndall beam test, or a significantly positive turbidity and did not result in any significant change in pH, regardless of container.

conclusionPer the protocol used in this study, glycopyrrolate and rocuronium were determined to be physically compatible.

Indexed as

GlycopyrrolateHumansRocuroniumGlycopyrrolateRocuroniumDrug compatibilityDrug interactionsGlycopyrrolateIntravenous administrationRocuronium

Identifiers

PMID37379091
PMCPMC10328188
OpenAlexW4382344682

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.