ArticleJournal of cancer research and clinical oncology2023
Are sleep disorders associated with the risk of gastrointestinal cancer?-A case-control study.
Article in Journal of cancer research and clinical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 17 citations in OpenAlex.
- Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review).International journal of molecular medicine · 2026Review
- Electroencephalogram-guided anesthesia and postoperative anxiety and depression in elderly gastric cancer patients with sleep disorders.World journal of psychiatry · 2026Article
- Sex-Related Differences in the Association Between Sleep Apnea and Subsequent Urinary Incontinence Diagnosis.Clocks & sleep · 2025Article
- Evaluating the psychosocial effects of cancer on sleep quality and mental health in elderly populations.BMC psychiatry · 2025Article
- Investigation of gastrointestinal tumor symptoms and risk factors in eighty patients with Parkinson's disease.World journal of gastrointestinal oncology · 2025Article
- Risk of Biliary Tract and Pancreatic Cancer Following Obstructive Sleep Apnea Diagnosis: Analysis of a National Health Insurance Database.Journal of rhinology : official journal of the Korean Rhinologic Society · 2025Article
- Sleep disorders in cancer: interactions and intrinsic links.Frontiers in oncology · 2025Review
- Sleep health: an unappreciated key player in colorectal cancer.Journal of Cancer · 2025Review
- Impaired sleep efficiency predicts adverse prognosis in elderly pancreatic cancer patients: a retrospective case - control study based on wearable smart devices.American journal of translational research · 2025Article
- Common Risk Factors in Gastrointestinal Cancers: A Narrative Review.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2025Review
- The Incidence and Influencing Factors of Sleep Disorders in Cyber Knife Patients during Treatment.Actas espanolas de psiquiatria · 2024Article
- Impact of sleep on gastrointestinal cancer.World journal of clinical oncology · 2024Article
- Investigation of Common Pathways and Putative Biomarker Candidates of Colorectal Cancer and Insomnia by Using IntegrativeIranian journal of biotechnology · 2024Article
- Article
- Prevalence and bidirectional association of sleep quality and gut health among Chinese midwives: a large population, multi-center cross-sectional study.Frontiers in public health · 2024Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSleep disorders are among the most common health problems worldwide and are linked to a variety of physical and mental health problems. Recently, there has been increasing evidence of an association between sleep disorders and cancer risk. We aimed to investigate this association specifically for cancers of the gastrointestinal (GI) tract.
methodsUsing the DA database (IQVIA), adult patients diagnosed with GI cancer between January 2010 and December 2022 were retrospectively compared to a 1:1 propensity score-matched cohort of patients without cancer. The outcome of the study was the association between sleep disorders and subsequent diagnosis of GI cancer. To determine whether sleep disorders were more common in patients with GI cancer than in patients without GI cancer, logistic regression models were used to estimate odds ratios (ORs) with 95% confidence intervals (95% CI).
resultsAfter matching, 37,161 cases with GI cancer and 37,161 controls without cancer were available for analysis. No association with cancer was found for sleep disorders in the overall history before the index date (OR 1.04; 95% CI 0.96-1.12), but considering sleep disorders documented within 1 year before the index date showed a positive association with GI cancer overall (OR 1.20; 95% CI 1.08-1.34). Stratified analyses by cancer site revealed higher odds of sleep disorders prior to diagnosis of gastric, pancreatic, and colorectal cancer.
conclusionOur findings suggest that sleep disorders might be indicative of short-term health outcomes, including GI cancer, suggesting a role for sleep disorder screening in the context of cancer prevention efforts.
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