Evidence map›Paper›PMID 37378303›Full record

ArticleClinical, cosmetic and investigational dermatology2023

Association Between Skin Acid Mantle, Natural Moisturizing Factors, and Antibacterial Activity Against

Rui Li, MyriamRubecca Rodrigues, Lijuan Li, Jason Winget, Yu Wang, Caroline Wang, Ed Smith, Karl Wei

Open access · goldAbstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rui LiBeauty Revealed, Procter & Gamble International Operations SA SG Branch, Singapore, Singapore.ORCID 0000-0001-5796-2778
MyriamRubecca RodriguesBeauty Revealed, Procter & Gamble International Operations SA SG Branch, Singapore, Singapore.ORCID 0000-0003-1267-0856
Lijuan LiCorporate Functions Analytical, Procter & Gamble Mason Business Center, Cincinnati, OH, USA.
Jason WingetCorporate Functions Analytical, Procter & Gamble Mason Business Center, Cincinnati, OH, USA.
Yu WangBeauty Revealed, Procter & Gamble International Operations SA SG Branch, Singapore, Singapore.
Caroline WangBeauty Revealed, Procter & Gamble International Operations SA SG Branch, Singapore, Singapore.
Ed SmithPersonal Care, Procter & Gamble Mason Business Center, Cincinnati, OH, USA.
Karl WeiPersonal Care, Procter & Gamble Mason Business Center, Cincinnati, OH, USA.
Procter & Gamble (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The skin has evolved a system to prevent pathogenic microorganism colonization and infection. This study examined the role of natural moisturizing factors (NMFs) and skin pH on Study Population and Methods: A survey study with 82 female participants was performed. Participants maintained their daily hygiene routine, except for refraining from using leave-on products on their forearms on the day of the test. Skin sampling was performed using adhesive tapes. An ex vivo method was developed to study the viability and growth of Results: Heterogeneity of Conclusion: The results indicate that PCA, one of the NMFs in human skin, plays an important role in regulating the human skin acid mantle in vivo and contributes to antibacterial activity against

Indexed as

2-pyrrolidone-5-carboxylic acidskin acid mantleskin barrier functionskin moisturizerskin pHStaphylococcus aureus

Identifiers

PMID37378303
PMCPMC10292209
OpenAlexW4381685146

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.