Evidence map›Paper›PMID 37377944›Full record

ArticleTherapeutic advances in urology

Instrumental dead space and proximal working channel connector design in flexible ureteroscopy: a new concept.

Jia-Lun Kwok, Vincent De Coninck, Amelia Pietropaolo, Patrick Juliebø-Jones, Eugenio Ventimiglia, Thomas Tailly, Florian Alexander Schmid, Manuela Hunziker, Cédric Poyet, Olivier Traxer and 2 more

Abstract read
In one paragraph

Article in Therapeutic advances in urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jia-Lun KwokDepartment of Urology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-9758-6225
Vincent De ConinckDepartment of Urology, AZ Klina, Brasschaat, Belgium.
Amelia PietropaoloDepartment of Urology, University Hospital Southampton, Southampton, UK.ORCID https://orcid.org/0000-0001-7631-3108
Patrick Juliebø-JonesDepartment of Urology, Haukeland University Hospital, Bergen, Norway.ORCID https://orcid.org/0000-0003-4253-1283
Eugenio VentimigliaDivision of Experimental Oncology/Unit of Urology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.
Thomas TaillyDepartment of Urology, University Hospital Ghent, Ghent, Belgium.
Florian Alexander SchmidDepartment of Urology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Manuela HunzikerDepartment of Urology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Cédric PoyetDepartment of Urology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Olivier TraxerSorbonne Université, GRC n°20, Groupe de Recherche Clinique sur la Lithiase Urinaire, Hôpital Tenon, F-75020, Paris, France.
Daniel EberliDepartment of Urology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Etienne Xavier KellerDepartment of Urology, University Hospital Zurich, University of Zurich, Frauenklinikstrasse 10, CH-8091 Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective of this study was to evaluate a new concept in flexible ureteroscopy: instrumental dead space (IDS). For this purpose, various proximal working channel connector designs, as well as the impact of ancillary devices occupying the working channel were evaluated in currently available flexible ureteroscopes. Design and methods: IDS was defined as the volume of saline irrigation needed to inject at the proximal connector for delivery at the distal working channel tip. Because IDS is related to working channel diameter and length, proximal connector design, as well as occupation of working channel by ancillary devices, these parameters were also reviewed. Results: IDS significantly varied between flexible ureteroscope models, ranging from 1.1 ml for the Pusen bare scopes, to 2.3 ml for Olympus scopes with their 4-way connector ( Conclusions: IDS appears as a new parameter that should be considered for future applications of flexible ureteroscopes. A low IDS seems desirable for several clinical applications. The main factors impacting IDS are working channel and proximal connector design, as well as ancillary devices inserted into the working channel. Future studies should clarify how reducing IDS may affect irrigation flow, intrarenal pressure, and direct in-scope suction, as well as evaluate the most desirable proximal connector design properties.

Indexed as

connector designinstrumental dead spaceLuer lockstone dust aspirationureteroscopy

Identifiers

PMID37377944
PMCPMC10291398

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.