Evidence map›Paper›PMID 37377921›Full record

ArticleFrontiers in oncology2023

Longitudinal characterization of primary osteosarcoma and derived subcutaneous and orthotopic relapsed patient-derived xenograft models.

Maria Eugenia Marques da Costa, Robin Droit, Pierre Khneisser, Anne Gomez-Brouchet, Tiphaine Adam-de-Beaumais, Marie Nolla, Nicolas Signolles, Jacob Torrejon, Bérangère Lombard, Damarys Loew and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Biological Sample Collection to Advance Research and Treatment: A Fight Osteosarcoma Through European Research and Euro Ewing Consortium Statement.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Guideline
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Maria Eugenia Marques da CostaINSERM U1015, Université Paris-Saclay, Villejuif, France.
Robin DroitINSERM U1015, Université Paris-Saclay, Villejuif, France.
Pierre KhneisserDepartment of Medical Biology and Pathology, Gustave Roussy Cancer Campus, Villejuif, France.
Anne Gomez-BrouchetDepartment of Pathology, IUCT-Oncopole, CHU Toulouse and University Toulouse, Pharmacology and Structural Biology Institute, CNRS UMR5089, Toulouse, France.
Tiphaine Adam-de-BeaumaisDepartment of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France.
Marie NollaDepartment of Pediatric Hemato-oncology, CHU Toulouse, Toulouse, France.
Nicolas SignollesDepartment of Medical Biology and Pathology, Gustave Roussy Cancer Campus, Villejuif, France.
Jacob TorrejonInstitut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France.
Bérangère LombardInstitut Curie, PSL Research University, Centre de Recherche, Laboratoire de Spectrométrie de Masse Protéomique, Paris, France.
Damarys LoewInstitut Curie, PSL Research University, Centre de Recherche, Laboratoire de Spectrométrie de Masse Protéomique, Paris, France.
Olivier AyraultInstitut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France.
Jean-Yves ScoazecDepartment of Medical Biology and Pathology, Gustave Roussy Cancer Campus, Villejuif, France.
Birgit GeoergerINSERM U1015, Université Paris-Saclay, Villejuif, France.
Gilles VassalDepartment of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France.
Antonin MarchaisINSERM U1015, Université Paris-Saclay, Villejuif, France.
Nathalie GasparINSERM U1015, Université Paris-Saclay, Villejuif, France.
Institut Gustave Roussy · FRUniversité Paris-Saclay · FRInstitut Curie · FRCentre Hospitalier Universitaire de Toulouse · FRCentre National de la Recherche Scientifique · FRInserm · FRUniversité Paris Sciences et Lettres · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma is a rare bone cancer in adolescents and young adults with a dismal prognosis because of metastatic disease and chemoresistance. Despite multiple clinical trials, no improvement in outcome has occurred in decades. There is an urgent need to better understand resistant and metastatic disease and to generate

Indexed as

boneomicsosteosarcomapatient-derived xenograftRNAseq

Identifiers

PMID37377921
PMCPMC10291137
OpenAlexW4380264772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.