Evidence map›Paper›PMID 37377040›Full record

ArticleAutism research : official journal of the International Society for Autism Research2023

Health conditions in autism: Defining the trajectory from adolescence to early adulthood.

Beth A Malow, Yinge Qian, Jennifer L Ames, Stacey Alexeeff, Lisa A Croen

Open access · bronzeAbstract read
In one paragraph

Article in Autism research : official journal of the International Society for Autism Research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Young Adulthood Milestones and Supports Within the Context of Autism.Journal of autism and developmental disorders · 2025
    Article
  9. Article
  10. Article
  11. Comparative Analysis of Autistic Women Across the Lifespan: Childhood vs. Adulthood Diagnosis.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  12. Article
  13. Article
  14. Trajectories of positive affect in autistic individuals during the transition to adulthood.Autism : the international journal of research and practice · 2025
    Article
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Beth A MalowSleep Disorders Division, Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-1624-7636
Yinge QianDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Jennifer L AmesDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.ORCID 0000-0003-0906-9162
Stacey AlexeeffDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Lisa A CroenDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.ORCID 0000-0001-7849-9428
Kaiser Permanente · USVanderbilt University Medical Center · US

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lea K Davis · 2020 to 2026
$10.3M
Harnessing Electronic Health Records to Identify Participants and to Study Health Outcomes in Transition-Age Youth and Adults with Autism Spectrum DisorderK18MH122755 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MALOW, BETH A · 2020 to 2021
$340k
NICHD NIH HHS P50 HD103537NIMH NIH HHS K18 MH122755NIMH NIH HHS K18MH122755
6 · The paper itself

Abstract

Autistic adults, as compared to non-autistic adults, have increased rates of nearly all medical and psychiatric conditions. Many of these conditions begin in childhood, although few longitudinal studies have been conducted to examine prevalence rates of these conditions from adolescence into early adulthood. In this study, we analyze the longitudinal trajectory of health conditions in autistic youth, compared to age and sex-matched non-autistic youth, transitioning from adolescence into early adulthood in a large integrated health care delivery system. The percent and modeled prevalence of common medical and psychiatric conditions increased from age 14 to 22 years, with autistic youth having a higher prevalence of most conditions than non-autistic youth. The most prevalent conditions in autistic youth at all ages were obesity, neurological disorders, anxiety, and ADHD. The prevalence of obesity and dyslipidemia rose at a faster rate in autistic youth compared to non-autistic youth. By age 22, autistic females showed a higher prevalence of all medical and psychiatric conditions compared to autistic males. Our findings emphasize the importance of screening for medical and psychiatric conditions in autistic youth, coupled with health education targeted at this population, to mitigate the development of adverse health outcomes in autistic adults.

Indexed as

Autism Spectrum DisorderAutistic DisorderAdolescentAdultAnxietyAnxiety DisordersFemaleHumansMaleObesityYoung Adultadolescentsadultsautismelectronic medical recordshealth conditions

Identifiers

PMID37377040
PMCPMC10524876
OpenAlexW4382345167

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.