Evidence map›Paper›PMID 37377008›Full record

ArticleEuropean heart journal2023

Statins for ACTA2 mutation-driven atherosclerosis?

Hanrui Zhang, Benedek Halmos, Marit Westerterp

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in European heart journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Hanrui ZhangCardiometabolic Genomics Program, Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, 630 West 168th Street, P&S 10-401 New York, NY 10032, USA.ORCID 0000-0001-8655-938X
Benedek HalmosDepartment of Pediatrics, University Medical Center Groningen, University of Groningen, Antonius Deusinglaan 1, Groningen 9713AV, The Netherlands.ORCID 0000-0002-6010-5096
Marit WesterterpDepartment of Pediatrics, University Medical Center Groningen, University of Groningen, Antonius Deusinglaan 1, Groningen 9713AV, The Netherlands.ORCID 0000-0003-2230-1659

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Integrative genomic and functional genomic studies to connect variant to function for CAD GWAS lociR01HL168174 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Wei Li, EDOARDO MARCORA · 2023 to 2026
$3.1M
Discovering Wdfy3 as a novel regulator of macrophage efferocytosis by genome-wide CRISPR screenR01HL151611 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ZHANG, HANRUI · 2020 to 2024
$3.0M
Macrophage-specific function of GWAS CAD-associated LIPA alleles in atherosclerosisR00HL130574 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ZHANG, HANRUI · 2018 to 2020
$733k
NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1TR001873NHLBI NIH HHS R01 HL151611NHLBI NIH HHS R01 HL168174NIH HHS R00HL130574
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AtherosclerosisHydroxymethylglutaryl-CoA Reductase InhibitorsActinsCholesterolHumansMuscle, SmoothMutationMyocytes, Smooth MuscleACTA2 protein, humanActinsCholesterolHydroxymethylglutaryl-CoA Reductase Inhibitors

Identifiers

PMID37377008
PMCPMC10393068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.