Evidence map›Paper›PMID 37376598›Full record

ArticleViruses2023

Significant Broad-Spectrum Antiviral Activity of Bi121 against Different Variants of SARS-CoV-2.

Bobban Subhadra, Ragini Agrawal, Virender Kumar Pal, Agnes-Laurence Chenine, Jeffy George Mattathil, Amit Singh

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Bobban SubhadraBiom Pharmaceutical Corporation, 2203 Industrial Blvd, Sarasota, FL 34234, USA.
Ragini AgrawalDepartment of Microbiology and Cell Biology, Center for Infectious Disease Research, Indian Institute of Science (IISc), CV Raman Ave., Bengaluru 560012, India.
Virender Kumar PalDepartment of Microbiology and Cell Biology, Center for Infectious Disease Research, Indian Institute of Science (IISc), CV Raman Ave., Bengaluru 560012, India.
Agnes-Laurence ChenineIntegrated BioTherapeutics Inc., 4 Research Court, Suite 300, Rockville, MD 20850, USA.
Jeffy George MattathilIntegrated BioTherapeutics Inc., 4 Research Court, Suite 300, Rockville, MD 20850, USA.ORCID 0000-0003-1144-9244
Amit SinghDepartment of Microbiology and Cell Biology, Center for Infectious Disease Research, Indian Institute of Science (IISc), CV Raman Ave., Bengaluru 560012, India.ORCID 0000-0001-6761-1664
Indian Institute of Science Bangalore · INIntegrated BioTherapeutics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has so far infected 762 million people with over 6.9 million deaths worldwide. Broad-spectrum viral inhibitors that block the initial stages of infection by reducing virus binding and proliferation, thereby reducing disease severities, are still an unmet global medical need. We studied Bi121, which is a standardized polyphenolic-rich compound isolated from

Indexed as

COVID-19SARS-CoV-2AnimalsAntiviral AgentsChlorocebus aethiopsHumansSpike Glycoprotein, CoronavirusTandem Mass SpectrometryVero CellsVesiculovirusAntiviral AgentsSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2antiviralBi121COVID-19intercalating agentNeoilludin BPelargonium sidoidesSARS-CoV-2

Identifiers

PMID37376598
PMCPMC10305169
OpenAlexW4379055566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.