Evidence map›Paper›PMID 37376486›Full record

ArticleVaccines2023

Common Adverse Events from Mixing COVID-19 Vaccine Booster in Hanoi, Vietnam.

Pham Van Hung, Thai Duy Nguyen, Luu Thi Ha, Phung Lam Toi, Tran Hong Tram

Abstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pham Van HungNational Institute for Control of Vaccine and Biologicals, Hanoi 100000, Vietnam.
Thai Duy NguyenNational Institute for Control of Vaccine and Biologicals, Hanoi 100000, Vietnam.ORCID 0000-0003-3997-2846
Luu Thi HaInstitute of Reproductive and Child Health/Ministry of Health Key Laboratory of Reproductive Health and Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, China.ORCID 0009-0006-3841-9685
Phung Lam ToiHealth Strategy and Policy Institute, Ministry of Health, Hanoi 100000, Vietnam.ORCID 0000-0002-8326-388X
Tran Hong TramNational Institute for Control of Vaccine and Biologicals, Hanoi 100000, Vietnam.ORCID 0009-0006-3517-6112

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMixing vaccines was proposed as a solution to tackle supply chain interruptions during the crisis of the COVID-19 pandemic. This study aimed to investigate the safety of mixing COVID-19 vaccines for a booster dose in Hanoi, Vietnam.

methodA cross-sectional study was conducted via a telephone-based interview to identify the adverse events following COVID-19 vaccination among 719 participants in Hanoi, Vietnam.

resultsIn total, 45.76% of participants experienced at least one adverse event following two doses of the COVID-19 vaccine. Most of the adverse events were local effects with mild symptoms such as fever, headache, muscle pain, and/or pain at the site. In general, matching two doses in the same vaccines was not associated with the adverse events as compared to mixing vaccines (OR = 1.43, 96%CI: 0.93-2.2), except matching two doses of Pfizer (OR = 2.25, 95%CI: 1.33-3.82).

conclusionThe findings of this study suggest the overall safety of mixed vaccination. In light of the vaccine shortage, mixing vaccinations for COVID-19 prevention is a good solution. Further studies with larger cohorts and investigating immunity following mixing vaccines are needed to elucidate the mechanism.

Indexed as

adverse eventsCOVID-19matchingmixingvaccineVietnam

Identifiers

PMID37376486
PMCPMC10304128

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.