Evidence map›Paper›PMID 37376399›Full record

ArticlePolymers2023

Self-Assembled CNF/rGO/Tannin Composite: Study of the Physicochemical and Wound Healing Properties.

Katherina Fernández, Aylen Llanquileo, Monserrat Bustos, Valentina Aedo, Isleidy Ruiz, Sebastián Carrasco, Mauricio Tapia, Miguel Pereira, Manuel F Meléndrez, Claudio Aguayo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Katherina FernándezLaboratorio de Biomateriales, Departamento de Ingeniería Química, Facultad de Ingeniería, Universidad de Concepción, Concepción 4070386, Chile.ORCID 0000-0002-0403-7164
Aylen LlanquileoLaboratorio de Biomateriales, Departamento de Ingeniería Química, Facultad de Ingeniería, Universidad de Concepción, Concepción 4070386, Chile.
Monserrat BustosLaboratorio de Biomateriales, Departamento de Ingeniería Química, Facultad de Ingeniería, Universidad de Concepción, Concepción 4070386, Chile.
Valentina AedoLaboratorio de Biomateriales, Departamento de Ingeniería Química, Facultad de Ingeniería, Universidad de Concepción, Concepción 4070386, Chile.
Isleidy RuizLaboratorio de Biomateriales, Departamento de Ingeniería Química, Facultad de Ingeniería, Universidad de Concepción, Concepción 4070386, Chile.
Sebastián CarrascoLaboratorio de Biomateriales, Departamento de Ingeniería Química, Facultad de Ingeniería, Universidad de Concepción, Concepción 4070386, Chile.
Mauricio TapiaLaboratorio de Biomateriales, Departamento de Ingeniería Química, Facultad de Ingeniería, Universidad de Concepción, Concepción 4070386, Chile.
Miguel PereiraLaboratorio de Productos Forestales, Departamento de Ingeniería Química, Facultad de Ingeniería, Universidad de Concepción, Concepción 4070386, Chile.ORCID 0000-0003-0618-6259
Manuel F MeléndrezGrupo Interdisciplinario de Nanotecnología Aplicada (GINA), Laboratorio de Materiales Híbridos (HML), Departamento de Ingeniería de Materiales (DIMAT), Facultad de Ingeniería, Universidad de Concepción, Concepción 4070386, Chile.ORCID 0000-0002-5826-4979
Claudio AguayoDepartmento de Inmunología y Bioquímica Clínica, Facultad de Farmacia, Universidad de Concepción, Concepción 4070386, Chile.ORCID 0000-0003-4565-9602
Leonard I AtanaseFaculty of Medical Dentistry, Apollonia University of Iasi, 700511 Iasi, Romania.ORCID 0000-0002-3657-1492
University of Concepción · CLApollonia University · RO

Funding

Agencia Nacional de Investigación y Desarrollo 1210770
6 · The paper itself

Abstract

In this study, a conductive composite material, based on graphene oxide (GO), nanocellulose (CNF), and tannins (TA) from pine bark, reduced using polydopamine (PDA), was developed for wound dressing. The amount of CNF and TA was varied in the composite material, and a complete characterization including SEM, FTIR, XRD, XPS, and TGA was performed. Additionally, the conductivity, mechanical properties, cytotoxicity, and in vitro wound healing of the materials were evaluated. A successful physical interaction between CNF, TA, and GO was achieved. Increasing CNF amount in the composite reduced the thermal properties, surface charge, and conductivity, but its strength, cytotoxicity, and wound healing performance were improved. The TA incorporation slightly reduced the cell viability and migration, which may be associated with the doses used and the extract's chemical composition. However, the in-vitro-obtained results demonstrated that these composite materials can be suitable for wound healing.

Indexed as

graphene oxidenanocellulosepolydopaminereduced graphene oxidewound healing

Identifiers

PMID37376399
PMCPMC10304054
OpenAlexW4381662658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.