Evidence map›Paper›PMID 37376125›Full record

ReviewPharmaceutics2023

"Bioinspired" Membrane-Coated Nanosystems in Cancer Theranostics: A Comprehensive Review.

Nimeet Desai, Dhwani Rana, Shreya Pande, Sagar Salave, Jyotsnendu Giri, Derajram Benival, Nagavendra Kommineni

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nimeet DesaiDepartment of Biomedical Engineering, Indian Institute of Technology Hyderabad, Kandi 502285, India.ORCID 0000-0002-3575-6671
Dhwani RanaNational Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad 382355, India.ORCID 0000-0002-1591-9226
Shreya PandeDepartment of Biomedical Engineering, Indian Institute of Technology Hyderabad, Kandi 502285, India.ORCID 0000-0003-0344-3598
Sagar SalaveNational Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad 382355, India.ORCID 0000-0003-3000-1998
Jyotsnendu GiriDepartment of Biomedical Engineering, Indian Institute of Technology Hyderabad, Kandi 502285, India.
Derajram BenivalNational Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad 382355, India.
Nagavendra KommineniCenter for Biomedical Research, Population Council, New York, NY 10065, USA.ORCID 0000-0003-4771-7925

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Achieving precise cancer theranostics necessitates the rational design of smart nanosystems that ensure high biological safety and minimize non-specific interactions with normal tissues. In this regard, "bioinspired" membrane-coated nanosystems have emerged as a promising approach, providing a versatile platform for the development of next-generation smart nanosystems. This review article presents an in-depth investigation into the potential of these nanosystems for targeted cancer theranostics, encompassing key aspects such as cell membrane sources, isolation techniques, nanoparticle core selection, approaches for coating nanoparticle cores with the cell membrane, and characterization methods. Moreover, this review underscores strategies employed to enhance the multi-functionality of these nanosystems, including lipid insertion, membrane hybridization, metabolic engineering, and genetic modification. Additionally, the applications of these bioinspired nanosystems in cancer diagnosis and therapeutics are discussed, along with the recent advances in this field. Through a comprehensive exploration of membrane-coated nanosystems, this review provides valuable insights into their potential for precise cancer theranostics.

Indexed as

cancercell membranemembrane coatingnanoparticlestheranosticstumor targeting

Identifiers

PMID37376125
PMCPMC10303942

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.