Evidence map›Paper›PMID 37376063›Full record

ReviewPharmaceutics2023

Immunomodulatory Effect and Biological Significance of β-Glucans.

Xuemei Zhong, Guoqing Wang, Fu Li, Sixian Fang, Siai Zhou, Akihiro Ishiwata, Alexander G Tonevitsky, Maxim Shkurnikov, Hui Cai, Feiqing Ding

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
49.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 124 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Environmental Benefits of Yeast PostbioticAnimals : an open access journal from MDPI · 2026
    Article
  7. A β‑1,3‑1,6‑glucan fromMolecular medicine reports · 2026
    Article
  8. Review
  9. Review
  10. Review
  11. β-Glucans,Journal of fungi (Basel, Switzerland) · 2026
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Xuemei ZhongSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus, Sun Yat-sen University, Shenzhen 518107, China.
Guoqing WangSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus, Sun Yat-sen University, Shenzhen 518107, China.
Fu LiThe Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen 518033, China.
Sixian FangSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus, Sun Yat-sen University, Shenzhen 518107, China.
Siai ZhouSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus, Sun Yat-sen University, Shenzhen 518107, China.
Akihiro IshiwataRIKEN Cluster for Pioneering Research, Wako 351-0198, Saitama, Japan.ORCID 0000-0002-5542-2214
Alexander G TonevitskyFaculty of Biology and Biotechnology, National Research University Higher School of Economics, Moscow 117418, Russia.
Maxim ShkurnikovFaculty of Biology and Biotechnology, National Research University Higher School of Economics, Moscow 117418, Russia.
Hui CaiSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus, Sun Yat-sen University, Shenzhen 518107, China.ORCID 0000-0002-5394-8167
Feiqing DingSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus, Sun Yat-sen University, Shenzhen 518107, China.ORCID 0000-0002-0211-7101
Sun Yat-sen University · CNNational Research University Higher School of Economics · RUPioneer (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-glucan, one of the homopolysaccharides composed of D-glucose, exists widely in cereals and microorganisms and possesses various biological activities, including anti-inflammatory, antioxidant, and anti-tumor properties. More recently, there has been mounting proof that β-glucan functions as a physiologically active "biological response modulator (BRM)", promoting dendritic cell maturation, cytokine secretion, and regulating adaptive immune responses-all of which are directly connected with β-glucan-regulated glucan receptors. This review focuses on the sources, structures, immune regulation, and receptor recognition mechanisms of β-glucan.

Indexed as

adjuvantsdendritic cellsimmune systemβ-glucans

Identifiers

PMID37376063
PMCPMC10302218
OpenAlexW4381570012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.