Evidence map›Paper›PMID 37376054›Full record

ArticlePharmaceutics2023

Solid Lipid Nanoparticles Containing Morin: Preparation, Characterization, and Ex Vivo Permeation Studies.

Federica De Gaetano, Consuelo Celesti, Giuseppe Paladini, Valentina Venuti, Maria Chiara Cristiano, Donatella Paolino, Daniela Iannazzo, Vincenza Strano, Anna M Gueli, Silvana Tommasini and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Federica De GaetanoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, V.le Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0001-9638-5520
Consuelo CelestiDepartment of Engineering, University of Messina, Contrada Di Dio, 98166 Messina, Italy.ORCID 0000-0003-1393-477X
Giuseppe PaladiniDepartment of Physics and Astronomy "Ettore Majorana", University of Catania, Via S. Sofia 64, 95123 Catania, Italy.ORCID 0000-0001-7446-0817
Valentina VenutiDepartment of Mathematical and Computer Sciences, Physical Sciences and Earth Sciences, University of Messina, V.le Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0003-2907-9165
Maria Chiara CristianoDepartment of Medical and Surgical Sciences, University of Catanzaro "Magna Graecia", V.le Europa s.n.c., 88100 Catanzaro, Italy.ORCID 0000-0002-5510-7599
Donatella PaolinoDepartment of Experimental and Clinical Medicine, University of Catanzaro "Magna Graecia", V.le Europa s.n.c., 88100 Catanzaro, Italy.ORCID 0000-0002-5223-9879
Daniela IannazzoDepartment of Engineering, University of Messina, Contrada Di Dio, 98166 Messina, Italy.ORCID 0000-0003-2190-0035
Vincenza StranoNational Council of Research, Institute of Microelectronics and Microsystems (CNR-IMM), University of Catania, Via S. Sofia 64, 95123 Catania, Italy.ORCID 0000-0003-2053-4141
Anna M GueliDepartment of Physics and Astronomy "Ettore Majorana", University of Catania, Via S. Sofia 64, 95123 Catania, Italy.
Silvana TommasiniDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, V.le Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.
Cinzia Anna VenturaDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, V.le Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0002-8743-2046
Rosanna StancanelliDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, V.le Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0002-8670-7685
University of Messina · ITUniversity of Catania · ITMagna Graecia University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, bioactive compounds have been the focus of much interest in scientific research, due to their low toxicity and extraordinary properties. However, they possess poor solubility, low chemical stability, and unsustainable bioavailability. New drug delivery systems, and among them solid lipid nanoparticles (SLNs), could minimize these drawbacks. In this work, morin (MRN)-loaded SLNs (MRN-SLNs) were prepared using a solvent emulsification/diffusion method, using two different lipids, Compritol

Indexed as

ex vivo permeationin vitro releasemorinphysical–chemical characterizationsolid lipid nanoparticles

Identifiers

PMID37376054
PMCPMC10300871
OpenAlexW4378588782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.