Evidence map›Paper›PMID 37376047›Full record

ArticlePharmaceutics2023

Cyclodextrins and Their Polymers Affect Human Serum Albumin's Interaction with Drugs Used in the Treatment of Pulmonary Infections.

Anna A Skuredina, Linara R Yakupova, Tatiana Yu Kopnova, Irina M Le-Deygen, Natalya G Belogurova, Elena V Kudryashova

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Anna A SkuredinaDepartment of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0003-0201-5495
Linara R YakupovaDepartment of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0002-5883-4687
Tatiana Yu KopnovaDepartment of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0001-5196-5863
Irina M Le-DeygenDepartment of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0002-6366-4491
Natalya G BelogurovaDepartment of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.
Elena V KudryashovaDepartment of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.
Lomonosov Moscow State University · RU

Funding

Russian Science Foundation 22-24-00604
6 · The paper itself

Abstract

Respiratory infectious diseases have challenged medical communities and researchers. Ceftriaxone, meropenem and levofloxacin are widely used for bacterial infection treatment, although they possess severe side effects. To overcome this, we propose cyclodextrin (CD) and CD-based polymers as a drug delivery system for the drugs under consideration. CD polymers demonstrate higher binding affinity for levofloxacin (Ka ≈ 10

Indexed as

antibacterial agentscyclodextrinshuman serum albuminpulmonary infections

Identifiers

PMID37376047
PMCPMC10301439
OpenAlexW4378471964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.