Evidence map›Paper›PMID 37376037›Full record

ArticlePharmaceutics2023

Nafcillin-Loaded Photocrosslinkable Nanocomposite Hydrogels for Biomedical Applications.

Gabriela Toader, Ionela Alice Podaru, Edina Rusen, Aurel Diacon, Raluca Elena Ginghina, Mioara Alexandru, Florina Lucica Zorila, Ana Mihaela Gavrila, Bogdan Trica, Traian Rotariu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Antimicrobial Hydrogel for Diabetic Wound Treatment.International journal of nanomedicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Gabriela ToaderMilitary Technical Academy, "Ferdinand I", 39-49 G. Cosbuc Blvd., 050141 Bucharest, Romania.ORCID 0000-0003-2647-9331
Ionela Alice PodaruMilitary Technical Academy, "Ferdinand I", 39-49 G. Cosbuc Blvd., 050141 Bucharest, Romania.ORCID 0000-0001-5478-4371
Edina RusenFaculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.
Aurel DiaconMilitary Technical Academy, "Ferdinand I", 39-49 G. Cosbuc Blvd., 050141 Bucharest, Romania.ORCID 0000-0001-5171-2049
Raluca Elena GinghinaResearch and Innovation Centre for CBRN Defense and Ecology, 225 Şos. Olteniţei, 041327 Bucharest, Romania.ORCID 0000-0003-1908-0234
Mioara AlexandruMicrobiology Laboratory, Horia Hulubei National Institute for R&D in Physics and Nuclear Engineering, 30 Reactorului St., 077125 Magurele, Romania.
Florina Lucica ZorilaMicrobiology Laboratory, Horia Hulubei National Institute for R&D in Physics and Nuclear Engineering, 30 Reactorului St., 077125 Magurele, Romania.ORCID 0000-0001-6042-8242
Ana Mihaela GavrilaNational Institute of Research, Development for Chemistry and Petrochemistry, 202 Splaiul Independentei, 060041 Bucharest, Romania.ORCID 0009-0009-2812-1633
Bogdan TricaNational Institute of Research, Development for Chemistry and Petrochemistry, 202 Splaiul Independentei, 060041 Bucharest, Romania.ORCID 0000-0002-9948-6914
Traian RotariuMilitary Technical Academy, "Ferdinand I", 39-49 G. Cosbuc Blvd., 050141 Bucharest, Romania.
Mariana IonitaFaculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.
Military Technical Academy · ROUniversitatea Națională de Știință și Tehnologie Politehnica București · ROHoria Hulubei National Institute for R and D in Physics and Nuclear Engineering · ROUniversity of Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin infections are frequently treated via intravenous or oral administration of antibiotics, which can lead to serious adverse effects and may sometimes contribute to the proliferation of resistant bacterial strains. Skin represents a convenient pathway for delivering therapeutic compounds, ensured by the high number of blood vessels and amount of lymphatic fluids in the cutaneous tissues, which are systematically connected to the rest of the body. This study provides a novel, straightforward method to obtain nafcillin-loaded photocrosslinkable nanocomposite hydrogels and demonstrates their performance as drug carriers and antimicrobial efficacy against Gram-positive bacteria. The novel formulations obtained, based on polyvinylpyrrolidone, tri(ethylene glycol) divinyl ether crosslinker, hydrophilic bentonite nanoclay, and/or two types of photoactive (TiO

Indexed as

drug deliveryhydrogelnafcillinnanocompositephotocrosslinkable

Identifiers

PMID37376037
PMCPMC10304380
OpenAlexW4378231292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.