Evidence map›Paper›PMID 37375837›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Inhibition of TRPA1, Endoplasmic Reticulum Stress, Human Airway Epithelial Cell Damage, and Ectopic

Tosifa A Memon, Lili Sun, Marysol Almestica-Roberts, Cassandra E Deering-Rice, Philip J Moos, Christopher A Reilly

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. CYP1B1 modulates stress and repair pathways in airway cells challenged by wood smoke particles.Toxicological sciences : an official journal of the Society of Toxicology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tosifa A MemonDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Utah Health, Salt Lake City, UT 84112, USA.
Lili SunDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Utah Health, Salt Lake City, UT 84112, USA.ORCID 0000-0002-6544-1945
Marysol Almestica-RobertsDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Utah Health, Salt Lake City, UT 84112, USA.
Cassandra E Deering-RiceDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Utah Health, Salt Lake City, UT 84112, USA.
Philip J MoosDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Utah Health, Salt Lake City, UT 84112, USA.
Christopher A ReillyDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Utah Health, Salt Lake City, UT 84112, USA.ORCID 0000-0002-5006-1982
University of Utah · US

Funding

TRP Channels and Air PollutionR01ES017431 · NIEHS · UNIVERSITY OF UTAH · PI REILLY, CHRISTOPHER A · 2009 to 2024
$5.3M
Pulmonary Epithelial TRPV3 and Wood Smoke InjuryR01ES027015 · NIEHS · UNIVERSITY OF UTAH · PI REILLY, CHRISTOPHER A · 2017 to 2021
$1.7M
NIEHS NIH HHS ES017431, ES027015NIEHS NIH HHS R01 ES017431NIEHS NIH HHS R01 ES027015
6 · The paper itself

Abstract

This study tested whether a medicinal plant, Vasaka, typically consumed as a tea to treat respiratory malaise, could protect airway epithelial cells (AECs) from wood smoke particle-induced damage and prevent pathological mucus production. Wood/biomass smoke is a pneumotoxic air pollutant. Mucus normally protects the airways, but excessive production can obstruct airflow and cause respiratory distress. Vasaka tea pre- and co-treatment dose-dependently inhibited mucin 5AC (

Indexed as

airway epitheliumbiomass smokelung injuryMUC5ACmucus hypersecretionTRPA1Vasakawood smoke

Identifiers

PMID37375837
PMCPMC10303053
OpenAlexW4381252248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.