Evidence map›Paper›PMID 37375763›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Selenylated Imidazo [1,2-

Giovana Bicudo Gomes, Claudia Stutz Zubieta, Jhefferson Dos Santos Guilhermi, Mônica Cristina Toffoli-Kadri, Adilson Beatriz, Jamal Rafique, Eduardo Benedetti Parisotto, Sumbal Saba, Renata Trentin Perdomo

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. NaphthaleneACS omega · 2025
    Article
  4. Following the Trace of Cyclodextrins on the Selenium and Tellurium Odyssey.International journal of molecular sciences · 2024
    Review
  5. HPW-Catalyzed environmentally benign approach to imidazo[1,2-Beilstein journal of organic chemistry · 2024
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Giovana Bicudo GomesPostgraduate Course in Pharmaceutical Sciences, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79070-900, Brazil.ORCID 0000-0002-9557-0959
Claudia Stutz ZubietaPostgraduate Course in Pharmaceutical Sciences, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79070-900, Brazil.
Jhefferson Dos Santos GuilhermiInstituto de Química (IQ), Universidade Federal de Goiás (UFG), Goiania 74690-900, Brazil.
Mônica Cristina Toffoli-KadriPostgraduate Course in Pharmaceutical Sciences, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79070-900, Brazil.
Adilson BeatrizLaboratory of Synthesis and Transformation of Organic Molecules (SINTMOL), Institute of Chemistry (INQUI), Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79074-460, Brazil.ORCID 0000-0001-6864-6092
Jamal RafiqueInstituto de Química (IQ), Universidade Federal de Goiás (UFG), Goiania 74690-900, Brazil.ORCID 0000-0002-2336-040X
Eduardo Benedetti ParisottoPostgraduate Course in Pharmaceutical Sciences, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79070-900, Brazil.ORCID 0000-0001-5934-0323
Sumbal SabaInstituto de Química (IQ), Universidade Federal de Goiás (UFG), Goiania 74690-900, Brazil.ORCID 0000-0002-6134-7249
Renata Trentin PerdomoPostgraduate Course in Pharmaceutical Sciences, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79070-900, Brazil.
Universidade Federal de Mato Grosso do Sul · BRUniversidade Federal de Goiás · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul 204/2022National Council for Scientific and Technological Development CNPq - 315399/2020-1, 422645/2021-4, 309975/2022-0, and 403210/2021-6
6 · The paper itself

Abstract

Colon cancer incidence rates are increasing annually, a scenario aggravated by genetic and epigenetic alterations that promote drug resistance. Recent studies showed that novel synthetic selenium compounds are more efficient and less toxic than conventional drugs, demonstrating biocompatibility and pro-oxidant effects on tumor cells. This study aimed to investigate the cytotoxic effect of MRK-107, an imidazo [1,2-

Indexed as

cancercell deathcytotoxicityoxidative damageROS generationselenium

Identifiers

PMID37375763
PMCPMC10302147
OpenAlexW4378906734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.