Evidence map›Paper›PMID 37375671›Full record

ArticleNutrients2023

The Combination of Binding Avidity of Ovomucoid-Specific IgE Antibody and Specific IgG4 Antibody Can Predict Positive Outcomes of Oral Food Challenges during Stepwise Slow Oral Immunotherapy in Children with Hen's Egg Allergy.

Shoichiro Taniuchi, Rika Sakai, Takahiro Nishida, Meguru Goma, Masatoshi Mitomori, Aya Imaide, Masahiro Enomoto, Masamitsu Nishino, Yo Okizuka, Hiroshi Kido

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Shoichiro TaniuchiDepartment of Pediatrics, Takatsuki General Hospital, Osaka 569-1192, Japan.ORCID 0000-0002-6369-3428
Rika SakaiDivision of Enzyme Chemistry, Institute for Enzyme Research, Tokushima University, Tokushima 770-8501, Japan.ORCID 0009-0005-0397-7559
Takahiro NishidaDepartment of Pediatrics, Takatsuki General Hospital, Osaka 569-1192, Japan.
Meguru GomaDepartment of Pediatrics, Takatsuki General Hospital, Osaka 569-1192, Japan.
Masatoshi MitomoriDepartment of Pediatrics, Takatsuki General Hospital, Osaka 569-1192, Japan.
Aya ImaideDepartment of Pediatrics, Takatsuki General Hospital, Osaka 569-1192, Japan.
Masahiro EnomotoDepartment of Pediatrics, Takatsuki General Hospital, Osaka 569-1192, Japan.
Masamitsu NishinoDepartment of Pediatrics, Takatsuki General Hospital, Osaka 569-1192, Japan.
Yo OkizukaDepartment of Pediatrics, Takatsuki General Hospital, Osaka 569-1192, Japan.
Hiroshi KidoDivision of Enzyme Chemistry, Institute for Enzyme Research, Tokushima University, Tokushima 770-8501, Japan.
Takatsuki General Hospital · JPTokushima University · JP

Funding

The Medical Research and Development Programs Focused on Technology Transfer of Japan Agency for Medical Research and Development #19ek0410048h0003 and 22he2302005h0004
6 · The paper itself

Abstract

To increase the prediction accuracy of positive oral food challenge (OFC) outcomes during stepwise slow oral immunotherapy (SS-OIT) in children with a hen's egg (HE) allergy, we evaluated the predictive value of the combination of antigen-specific IgE (sIgE) with antigen binding avidity and sIgG4 values. Sixty-three children with HE allergy undergoing SS-OIT were subjected to repeated OFCs with HE. We measured the ovomucoid (OVM)-sIgE by ImmunoCAP or densely carboxylated protein (DCP) microarray, sIgG4 by DCP microarray, and the binding avidity of OVM-sIgE defined as the level of 1/IC

Indexed as

Egg HypersensitivityAllergensAnimalsChickensFemaleImmunoglobulin EImmunoglobulin GOvomucinAllergensImmunoglobulin EImmunoglobulin GOvomucinhen’s egg allergyIgE binding avidityoral food challengeoral immunotherapyovomucoid-specific IgEovomucoid-specific IgG4

Identifiers

PMID37375671
PMCPMC10302081
OpenAlexW4380985970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.