Evidence map›Paper›PMID 37375667›Full record

ArticleNutrients2023

Real-World Management of High Stool Output in Patients with Short Bowel Syndrome: An International Multicenter Survey.

Narisorn Lakananurak, Elizabeth Wall, Hilary Catron, Adela Delgado, Sophie Greif, Jean Herlitz, Lisa Moccia, David Mercer, Tim Vanuytsel, Vanessa Kumpf and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Narisorn LakananurakDivision of Clinical Nutrition, Department of Medicine, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok 10330, Thailand.ORCID 0000-0003-3166-0856
Elizabeth WallClinical Nutrition, University of Chicago Medicine, Chicago, IL 60637, USA.
Hilary CatronCollege of Allied Health, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Adela DelgadoRoyal Alexandra Hospital, Alberta Health Services, Edmonton, AB T5H 3V9, Canada.
Sophie GreifDepartment of Hepatology and Gastroenterology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, 10117 Berlin, Germany.ORCID 0000-0003-1315-8766
Jean HerlitzClinical Nutrition, University of Chicago Medicine, Chicago, IL 60637, USA.
Lisa MocciaCenter for Human Nutrition, Cleveland Clinic, Cleveland, OH 44195, USA.
David MercerDepartment of Surgery, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Tim VanuytselGastroenterology and Hepatology, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-8728-0903
Vanessa KumpfCenter for Human Nutrition, Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID 0000-0002-3390-3869
Mark Berner-HansenDigestive Disease Center K, Bispebjerg University Hospital of Copenhagen, 2400 Copenhagen, Denmark.
Leah GramlichDepartment of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T5B 4E4, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInternational practice guidelines for high-stool-output (HSO) management in short bowel syndrome (SBS) are available, but data on implementation are lacking. This study describes the approach used to manage HSO in SBS patients across different global regions.

methodsThis is an international multicenter study evaluating medical management of HSO in SBS patients using a questionnaire survey. Thirty-three intestinal-failure centers were invited to complete the survey as one multidisciplinary team.

resultsSurvey response rate was 91%. Dietary recommendations varied based on anatomy and geographic region. For patients without colon-in-continuity (CiC), clinical practices were generally consistent with ESPEN guidelines, including separation of fluid from solid food (90%), a high-sodium diet (90%), and a low-simple-sugar diet (75%). For CiC patients, practices less closely followed guidelines, such as a low-fat diet (35%) or a high-sodium diet (50%). First-line antimotility and antisecretory medications were loperamide and proton-pump inhibitors. Other therapeutic agents (e.g., pancreatic enzymes and bile acid binders) were utilized in real-world practices, and usage varied based on intestinal anatomy.

conclusionExpert centers largely followed published HSO-management guidelines for SBS patients without CiC, but clinical practices deviated substantially for CiC patients. Determining the reasons for this discrepancy might inform future development of practice guidelines.

Indexed as

Short Bowel SyndromeDiet, Fat-RestrictedHumansIntestinesSodiumSurveys and QuestionnairesSodiumantimotility medicationantisecretory medicationdietary managementhigh stool outputintestinal failureshort bowel syndrome

Identifiers

PMID37375667
PMCPMC10305686

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.