Evidence map›Paper›PMID 37375550›Full record

ArticleNutrients2023

THC-Reduced

Joanna Bartkowiak-Wieczorek, Edyta Mądry, Michał Książkiewicz, Jakub Winkler-Galicki, Milena Szalata, Marlena Szalata, Ulises Elizalde Jiménez, Karolina Wielgus, Edmund Grześkowiak, Ryszard Słomski and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Joanna Bartkowiak-WieczorekPhysiology Department, Poznan University of Medical Sciences, ul. Święcickiego 6, 61-861 Poznań, Poland.ORCID 0000-0002-8347-0512
Edyta MądryPhysiology Department, Poznan University of Medical Sciences, ul. Święcickiego 6, 61-861 Poznań, Poland.ORCID 0000-0002-0081-6558
Michał KsiążkiewiczCannabitey s.c. Poznań, ul. Uniwersytetu Poznańskiego 10/B123, 61-614 Poznań, Poland.
Jakub Winkler-GalickiPhysiology Department, Poznan University of Medical Sciences, ul. Święcickiego 6, 61-861 Poznań, Poland.ORCID 0000-0003-1415-6252
Milena SzalataDepartment of Biotechnology, Institute of Natural Fibres and Medicinal Plants National Research Institute, Wojska Polskiego 71B, 60-630 Poznań, Poland.ORCID 0000-0003-1500-8251
Marlena SzalataDepartment of Biochemistry and Biotechnology, Poznań University of Life Sciences, ul. Dojazd 11, 60-632 Poznań, Poland.ORCID 0000-0002-0153-4317
Ulises Elizalde JiménezNeuromed Consultorios, José Ibarra Olivares 106, Centro, Pachuca de Soto 42000, Hidalgo, Mexico.ORCID 0009-0000-3717-8329
Karolina WielgusDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Szpitalna Street 27/33, 60-572 Poznań, Poland.ORCID 0000-0003-0629-2991
Edmund GrześkowiakDepartment of Clinical Pharmacy and Biopharmacy, Poznan University of Medical Sciences, ul. Rokietnicka 3, 60-806 Poznań, Poland.
Ryszard SłomskiDepartment of Biotechnology, Institute of Natural Fibres and Medicinal Plants National Research Institute, Wojska Polskiego 71B, 60-630 Poznań, Poland.ORCID 0000-0001-5601-7002
Agnieszka BienertDepartment of Clinical Pharmacy and Biopharmacy, Poznan University of Medical Sciences, ul. Rokietnicka 3, 60-806 Poznań, Poland.ORCID 0000-0001-7272-5738
Poznan University of Medical Sciences · PLInstitute of Natural Fibres and Medicinal Plants · PL

Funding

The National Centre for Research and Development INNOMED/I/11/NCBR/2014
6 · The paper itself

Abstract

The bioavailability levels of cannabidiol (CBD) and tetrahydrocannabinol (THC) determine their pharmacological effects. Therefore, for medical purposes, it is essential to obtain extracts containing the lowest possible content of the psychogenic component THC. In our extract, the CBD/THC ratio was 16:1, which is a high level compared to available medical preparations, where it is, on average, 1:1. This study assessed the bioavailability and stability of CBD and THC derived from

Indexed as

CannabidiolCannabinoidsCannabisAnimalsBiological AvailabilityPlant ExtractsPlant OilsPolyethylene GlycolsRatsRats, WistarSolventsCannabidiolCannabinoidscremophorPlant ExtractsPlant OilsPolyethylene GlycolsSolventsbioavailabilitycannabidiol (CBD)endocannabinoid systempharmacokineticstetrahydrocannabinol (THC)

Identifiers

PMID37375550
PMCPMC10304291
OpenAlexW4379795863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.