Evidence map›Paper›PMID 37375499›Full record

ArticlePathogens (Basel, Switzerland)2023

Stage-Dependent Increase of Systemic Immune Activation and CCR5

Abu Abudu Rahamani, Sacha Horn, Manuel Ritter, Anja Feichtner, Jubin Osei-Mensah, Vera Serwaa Opoku, Linda Batsa Debrah, Thomas F Marandu, Antelmo Haule, Jacklina Mhidze and 9 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Impact ofTropical medicine and infectious disease · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 8 institutions in 3 countries.

Abu Abudu RahamaniFilariasis Unit, Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), UPO, PMB, Kumasi 00233, Ghana.
Sacha HornDivision of Infectious Diseases and Tropical Medicine, University Hospital Munich, Ludwig-Maximilians-Universität (LMU), 80802 Munich, Germany.ORCID 0000-0001-7965-5728
Manuel RitterInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0001-8667-2067
Anja FeichtnerDivision of Infectious Diseases and Tropical Medicine, University Hospital Munich, Ludwig-Maximilians-Universität (LMU), 80802 Munich, Germany.
Jubin Osei-MensahFilariasis Unit, Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), UPO, PMB, Kumasi 00233, Ghana.ORCID 0000-0003-3470-2994
Vera Serwaa OpokuFilariasis Unit, Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), UPO, PMB, Kumasi 00233, Ghana.ORCID 0000-0001-7950-6650
Linda Batsa DebrahFilariasis Unit, Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), UPO, PMB, Kumasi 00233, Ghana.
Thomas F MaranduMbeya Medical Research Center (MMRC), Department of Immunology, National Institute for Medical Research (NIMR), Mbeya 53107, Tanzania.ORCID 0000-0002-3604-8511
Antelmo HauleMbeya Medical Research Center (MMRC), Department of Immunology, National Institute for Medical Research (NIMR), Mbeya 53107, Tanzania.
Jacklina MhidzeMbeya Medical Research Center (MMRC), Department of Immunology, National Institute for Medical Research (NIMR), Mbeya 53107, Tanzania.
Abdallah NgenyaNational Institute of Medical Research (NIMR)-Headquarters, Dar es Salaam 11101, Tanzania.
Max DemetriusNational Institute of Medical Research (NIMR)-Headquarters, Dar es Salaam 11101, Tanzania.
Ute Klarmann-SchulzInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn, 53127 Bonn, Germany.
Michael HoelscherDivision of Infectious Diseases and Tropical Medicine, University Hospital Munich, Ludwig-Maximilians-Universität (LMU), 80802 Munich, Germany.ORCID 0000-0002-7642-1835
Christof GeldmacherDivision of Infectious Diseases and Tropical Medicine, University Hospital Munich, Ludwig-Maximilians-Universität (LMU), 80802 Munich, Germany.
Achim HoeraufInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn, 53127 Bonn, Germany.
Akili KalingaNational Institute of Medical Research (NIMR)-Headquarters, Dar es Salaam 11101, Tanzania.ORCID 0000-0003-1884-3869
Alexander Y DebrahFilariasis Unit, Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), UPO, PMB, Kumasi 00233, Ghana.
Inge KroidlDivision of Infectious Diseases and Tropical Medicine, University Hospital Munich, Ludwig-Maximilians-Universität (LMU), 80802 Munich, Germany.
National Institute for Medical Research · TZKwame Nkrumah University of Science and Technology · GHGerman Center for Infection Research · DEUniversity Hospital Bonn · DEFraunhofer Institute for Translational Medicine and Pharmacology · DEKumasi Centre for Collaborative Research in Tropical Medicine · GHLudwig-Maximilians-Universität München · DEUniversity of Dar es Salaam · TZ

Funding

Deutsche Forschungsgemeinschaft HO2009/11-1Deutsche Forschungsgemeinschaft KR3615/1-1Federal Ministry of Education and Research 01KA1601Federal Ministry of Education and Research 01KA1612German Center for Infection Research TI03.907_00German Center for Infection Research TI07-003
6 · The paper itself

Abstract

Chronic lymphedema caused by infection of

Indexed as

CCR5CD4+ T cell activationCD8GhanaHLADR/CD38lymphatic filariasislymphedemaPD-1Tanzania

Identifiers

PMID37375499
PMCPMC10301430
OpenAlexW4379875660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.